RAB5 蛋白
Our Local Distributor
北京 101111
Quick Overview for RAB5 蛋白 (ABIN5776883)
抗原
See all RAB5 (RAB5A) 蛋白蛋白类型
生物活性
宿主
资源
纯度
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原理
- Rab5A, Ras-associated, small GTP-binding protein, rat, recombinant, E. coli
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Biological Activity Comment
- 100 pmol of protein can bind > 80 pmol of GDP.
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RAB5A, Member RAS Oncogene Family (RAB5A) (AA 1-215) protein (GST tag)
RAB5A 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
RAB5A, Member RAS Oncogene Family (RAB5A) protein (His tag)RAB5A 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >90% SDS, WB
RAB5A, Member RAS Oncogene Family (RAB5A) (AA 1-215) proteinRAB5A 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % pure SDS
RAB5A, Member RAS Oncogene Family (RAB5A) protein (Myc-DYKDDDDK Tag)RAB5A 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
RAB5A, Member RAS Oncogene Family (RAB5A) (AA 1-215), (full length) protein (His-SUMO Tag)RAB5A 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. SDS
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Supplied in 25 mM HEPES pH 7.240 mM NaCl2 mM MgCl210 μM GDP and 3 mM TCEP
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注意事项
- Please centrifuge briefly before opening (volume ≤2 ml).,avoid freeze/thaw cycles
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储存条件
- -80 °C
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储存方法
- store at -80 °C avoid freeze/thaw cycles
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有效期
- 12 months
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- RAB5 (RAB5A) (RAB5A, Member RAS Oncogene Family (RAB5A))
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别名
- Rab5A
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背景
- Rab5A is a small GTPase that belongs to the Ras superfamily. Rab proteins play an important role in various aspects of membrane traffic, including cargo selection, vesicle budding, vesicle motility, tethering, docking, and fusion. The small Rab5A GTPase is localized to plasma membrane, clathrin coated vesicles, caveosomes and early endosomes. Rab5 is a key regulator of the early endocytic pathway and plays a role in early endosome fusion and caveolar vesicle targeting to early endosomes. Furtermore it is also implicated in EGF receptor activation and apoptotic cell engulfment.
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分子量
- 24 kDa
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NCBI登录号
- NP_073183
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途径
- Smooth Muscle Cell Migration, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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