METRNL Protein (AA 46-311) (His tag)
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Quick Overview for METRNL Protein (AA 46-311) (His tag) (ABIN5714378)
抗原
See all METRNL 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- AA 46-311
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标记
- This METRNL protein is labelled with His tag.
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序列
- QYSSDRCSWK GSGLTHEAHR KEVEQVYLRC AAGAVEWMYP TGALIVNLRP NTFSPARHLT VCIRSFTDSS GANIYLEKTG ELRLLVPDGD GRPGRVQCFG LEQGGLFVEA TPQQDIGRRT TGFQYELVRR HRASDLHELS APCRPCSDTE VLLAVCTSDF AVRGSIQQVT HEPERQDSAI HLRVSRLYRQ KSRVFEPVPE GDGHWQGRVR TLLECGVRPG HGDFLFTGHM HFGEARLGCA PRFKDFQRMY RDAQERGLNP CEVGTD
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纯化方法
- SDS-PAGE
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Meteorin, Glial Cell Differentiation Regulator-Like (METRNL) (AA 46-311) protein (His tag)
METRNL 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB
Meteorin, Glial Cell Differentiation Regulator-Like (METRNL) (AA 46-311) protein (His-IF2DI Tag)METRNL 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1-2 mg/mL
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缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
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储存条件
- -80 °C,4 °C,-20 °C
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储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- METRNL (Meteorin, Glial Cell Differentiation Regulator-Like (METRNL))
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别名
- METRL
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背景
- Hormone induced following exercise or cold exposure that promotes energy expenditure. Induced either in the skeletal muscle after exercise or in adipose tissue following cold exposure and is present in the circulation. Able to stimulate energy expenditure associated with the browning of the white fat depots and improves glucose tolerance. Does not promote an increase in a thermogenic gene program via direct action on adipocytes, but acts by stimulating several immune cell subtypes to enter the adipose tissue and activate their prothermogenic actions. Stimulates an eosinophil-dependent increase in IL4 expression and promotes alternative activation of adipose tissue macrophages, which are required for the increased expression of the thermogenic and anti-inflammatory gene programs in fat. Required for some cold-induced thermogenic responses, suggesting a role in metabolic adaptations to cold tperatures .
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分子量
- 31.96 kDa
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UniProt
- Q641Q3
抗原
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