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METRNL Protein (AA 46-311) (His tag)

METRNL 宿主: 人 宿主: 酵母菌 Recombinant > 90 % SDS
产品编号 ABIN5714378
发货至: 中国
  • 抗原 See all METRNL 蛋白
    METRNL (Meteorin, Glial Cell Differentiation Regulator-Like (METRNL))
    蛋白类型
    Recombinant
    产品特性
    AA 46-311
    宿主
    • 3
    • 2
    • 1
    • 1
    • 1
    资源
    • 3
    • 2
    • 2
    • 1
    酵母菌
    标记
    This METRNL protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    序列
    QYSSDRCSWK GSGLTHEAHR KEVEQVYLRC AAGAVEWMYP TGALIVNLRP NTFSPARHLT VCIRSFTDSS GANIYLEKTG ELRLLVPDGD GRPGRVQCFG LEQGGLFVEA TPQQDIGRRT TGFQYELVRR HRASDLHELS APCRPCSDTE VLLAVCTSDF AVRGSIQQVT HEPERQDSAI HLRVSRLYRQ KSRVFEPVPE GDGHWQGRVR TLLECGVRPG HGDFLFTGHM HFGEARLGCA PRFKDFQRMY RDAQERGLNP CEVGTD
    纯化方法
    SDS-PAGE
    纯度
    > 90 %
    Top Product
    Discover our top product METRNL 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.1-2 mg/mL
    缓冲液
    20 mM Tris-HCl based buffer, pH 8.0
    储存条件
    -80 °C,4 °C,-20 °C
    储存方法
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 抗原
    METRNL (Meteorin, Glial Cell Differentiation Regulator-Like (METRNL))
    别名
    METRL (METRNL 产品)
    别名
    9430048M07Rik Protein, BC019776 Protein, fc90a08 Protein, fj23b04 Protein, wu:fc90a08 Protein, wu:fj23b04 Protein, zgc:56225 Protein, meteorin like, glial cell differentiation regulator Protein, meteorin, glial cell differentiation regulator-like Protein, meteorin-like, glial cell differentiation regulator Protein, meteorin, glial cell differentiation regulator-like L homeolog Protein, METRNL Protein, Metrnl Protein, metrnl.L Protein, metrnl Protein
    背景
    Hormone induced following exercise or cold exposure that promotes energy expenditure. Induced either in the skeletal muscle after exercise or in adipose tissue following cold exposure and is present in the circulation. Able to stimulate energy expenditure associated with the browning of the white fat depots and improves glucose tolerance. Does not promote an increase in a thermogenic gene program via direct action on adipocytes, but acts by stimulating several immune cell subtypes to enter the adipose tissue and activate their prothermogenic actions. Stimulates an eosinophil-dependent increase in IL4 expression and promotes alternative activation of adipose tissue macrophages, which are required for the increased expression of the thermogenic and anti-inflammatory gene programs in fat. Required for some cold-induced thermogenic responses, suggesting a role in metabolic adaptations to cold tperatures .
    分子量
    31.96 kDa
    UniProt
    Q641Q3
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