LCAT Protein (AA 25-433, partial) (His tag)
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Quick Overview for LCAT Protein (AA 25-433, partial) (His tag) (ABIN5712770)
抗原
See all LCAT 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- partial, AA 25-433
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标记
- This LCAT protein is labelled with His tag.
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序列
- FWLLNVLFPP HTTPKAELSN HTRPVILVPG CLGNQLEAKL DKPDVVNWMC YRKTEDFFTI WLDLNMFLPL GVDCWIDNTR VVYNRSSGLV SNAPGVQIRV PGFGKTYSVE YLDSSKLAGY LHTLVQNLVN NGYVRDETVR AAPYDWRLEP GQQEEYYRKL AGLVEEMHAA YGKPVFLIGH SLGCLHLLYF LLRQPQAWKD RFIDGFISLG APWGGSIKPM LVLASGDNQG IPIMSSIKLK EEQRITTTSP WMFPSRMAWP EDHVFISTPS FNYTGRDFQR FFADLHFEEG WYMWLQSRDL LAGLPAPGVE VYCLYGVGLP TPRTYIYDHG FPYTDPVGVL YEDGDDTVAT RSTELCGLWQ GRQPQPVHLL PLHGIQHLNM VFSNLTLEHI NAILLGAYRQ GPPASPTASP EPPPPE
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纯化方法
- SDS-PAGE
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Lecithin-Cholesterol Acyltransferase (LCAT) (AA 25-438) (Active) protein (His tag)
LCAT 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
Lecithin-Cholesterol Acyltransferase (LCAT) (AA 1-440) protein (GST tag)LCAT 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Lecithin-Cholesterol Acyltransferase (LCAT) proteinLCAT 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 85 % pure SDS
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1-2 mg/mL
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缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
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储存条件
- -80 °C,4 °C,-20 °C
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储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- LCAT (Lecithin-Cholesterol Acyltransferase (LCAT))
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别名
- LCAT
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背景
- Central enzyme in the extracellular metabolism of plasma lipoproteins. Synthesized mainly in the liver and secreted into plasma where it converts cholesterol and phosphatidylcholines (lecithins) to cholesteryl esters and lysophosphatidylcholines on the surface of high and low density lipoproteins (HDLs and LDLs). The cholesterol ester is then transported back to the liver. Has a preference for plasma 16:0-18:2 or 18:O-18:2 phosphatidylcholines. Also produced in the brain by primary astrocytes, and esterifies free cholesterol on nascent APOE-containing lipoproteins secreted from glia and influences cerebral spinal fluid (CSF) APOE- and APOA1 levels. Together with APOE and the cholesterol transporter ABCA1, plays a key role in the maturation of glial-derived, nascent lipoproteins. Required for rodeling high-density lipoprotein particles into their spherical forms.
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分子量
- 51.2 kDa
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UniProt
- P04180
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途径
- Lipid Metabolism
抗原
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