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MMP8 Protein (full length)

This Recombinant MMP8 protein is expressed in .
产品编号 ABIN2965548
发货至: 中国

Quick Overview for MMP8 Protein (full length) (ABIN2965548)

抗原

See all MMP8 蛋白
MMP8 (Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8))

蛋白类型

Recombinant

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应用范围

Activity Assay (AcA), Standard (STD)

纯度

> 90 % as determined by SDS-PAGE.
  • 产品特性

    full length

    产品特性

    Recombinant Human Matrix Metalloproteinase-8
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  • 应用备注

    Used as a standard for analyzing mammalian collagenase activity.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    The protein Solution (100 units/ml) in 0.05M Tris-HCl buffer, pH 7.6, containing 0.2M NaCl, 5mM CaCl2, 0.0025% NaN3 and 0.1% BSA.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • 抗原

    MMP8 (Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8))

    别名

    Matrix Metalloproteinase-8

    背景

    Matrix Metalloproteinase-8 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain having a molecular mass of 75 kDa. The MMP-8 is purified by proprietary chromatographic techniques. Introduction: Full-length recombinant human neutrophil pro-collagenase (MMP-8), latent form. Matrix metalloproteinase 8 (MMP-8), or neutrophil collagenase, degrades interstitial collagens, acting preferentially on collagen type I. Increased full-length MMP-8 protein was associated with infiltration into the skin of neutrophils, which are the major cell type that expresses MMP-8. MMP-8 is synthesized and stored in specific granules in neutrophil leukocytes. MMP-8 activity is therefore regulated by factors such as surface-bound ligands (IgG or complement components) that release it through degranulation. Once released and activated through proteolytic or oxidative mechanisms, MMP-8 plays a major role in the connective tissue turnover that accompanies inflammatory processes. Synonyms: Neutrophil collagenase, EC 3.4.24.34, Matrix metalloproteinase-8, MMP-8, PMNL collagenase, PMNL-CL, HNC, CLG1.
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