IL16 蛋白
Quick Overview for IL16 蛋白 (ABIN2830868)
抗原
See all IL16 蛋白蛋白类型
生物活性
宿主
资源
应用范围
纯度
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序列
- SAASASAASD ISVESKEATV CTVTLEKTSA GLGFSLEGGK GSLHGDKPLT INRIFKGTEQ GEMVQPGDEI LQLAGTAVQG LTRFEAWNVI KALPDGPVTI VIRRTSLQCK QTTASADS
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产品特性
- Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral T lymphocytes is in a concentration range of 1.0-100 ng/mL.
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过滤
- 0.2 μm filtered
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- PBS, pH 7.4
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储存条件
- -20 °C
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- IL16 (Interleukin 16 (IL16))
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别名
- Il16
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背景
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Relevance: Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4., Isoform 1 may act as a scaffolding protein that anchors ion channels in the membrane., Isoform 2 is involved in cell cycle progression in T-cells. Appears to be involved in transcriptional regulation of SKP2 and is probably part of a transcriptional repression complex on the core promoter of the SKP2 gene. May act as a scaffold for GABPB1 (the DNA-binding subunit the GABP transcription factor complex) and HDAC3 thus maintaining transcriptional repression and blocking cell cycle progression in resting T-cells.
Synonyms: IL-16, LCF,] -
分子量
- 12.2 kDa
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UniProt
- O54824
抗原
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