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IL16 蛋白

This Recombinant IL16 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN2830868
发货至: 中国
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Quick Overview for IL16 蛋白 (ABIN2830868)

抗原

See all IL16 蛋白
IL16 (Interleukin 16 (IL16))

蛋白类型

Recombinant

生物活性

Active

宿主

  • 20
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  • 1
  • 1
小鼠

资源

  • 31
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  • 1
大肠杆菌(E. Coli)

应用范围

Functional Studies (Func)

纯度

>98 % as determined by SDS-PAGE and HPLC.
  • 序列

    SAASASAASD ISVESKEATV CTVTLEKTSA GLGFSLEGGK GSLHGDKPLT INRIFKGTEQ GEMVQPGDEI LQLAGTAVQG LTRFEAWNVI KALPDGPVTI VIRRTSLQCK QTTASADS

    产品特性

    Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral T lymphocytes is in a concentration range of 1.0-100 ng/mL.

    过滤

    0.2 μm filtered
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    Conjugate His tag
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    PBS, pH 7.4

    储存条件

    -20 °C
  • 抗原

    IL16 (Interleukin 16 (IL16))

    别名

    Il16

    背景

    Relevance: Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4., Isoform 1 may act as a scaffolding protein that anchors ion channels in the membrane., Isoform 2 is involved in cell cycle progression in T-cells. Appears to be involved in transcriptional regulation of SKP2 and is probably part of a transcriptional repression complex on the core promoter of the SKP2 gene. May act as a scaffold for GABPB1 (the DNA-binding subunit the GABP transcription factor complex) and HDAC3 thus maintaining transcriptional repression and blocking cell cycle progression in resting T-cells.
    Synonyms: IL-16, LCF,]

    分子量

    12.2 kDa

    UniProt

    O54824
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