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VEGF 165 (Active) 蛋白

This Recombinant protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN2746009
发货至: 中国

Quick Overview for VEGF 165 (Active) 蛋白 (ABIN2746009)

抗原

VEGF 165

蛋白类型

Recombinant

生物活性

Active

宿主

  • 18
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资源

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大肠杆菌(E. Coli)

应用范围

SDS-PAGE (SDS)

纯度

>95 % (SDS-PAGE)
  • 原理

    VEGF 165 (human) (rec.)

    交叉反应

    产品特性

    Human VEGF 165 (165aa).

    内毒素水平

    <0.1ng/μg protein.

    Biological Activity Comment

    The ED50 for stimulation of cell proliferation in human umbilical vein endothelial cells by VEGF 165 has been determined to be in the range of 1-5ng/ml.
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  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstitute with 50 mM acetic acid to a concentration not lower than 50 μg/mL.

    注意事项

    After reconstitution, prepare aliquots and store at -20 °C. Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution. For long term storage we recommend to add at least 0.1 % human or bovine serum albumin.

    储存条件

    4 °C,-20 °C

    储存方法

    Short Term Storage: +4°C

    Long Term Storage: -20°C

    Use & Stability: Stable for at least 6 months after receipt when stored at -20°C.

    有效期

    6 months
  • 抗原

    VEGF 165

    背景

    Vascular Endothelial Growth Factor, VEGF-A, VPF

    Human vascular endothelial growth factor (VEGF 165) is produced as a homodimer. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. VEGF 165 is a specific mitogen for vascular endothelial cells and a strong angiogenic factor in vivo. In addition to its action as a mitogen it is a potent vascular permeability factor (VPF) in vivo. It is also a chemoattractant molecule for monocytes and endothelial cells. It induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels.

    分子量

    ~38.2kDa

    UniProt

    P15692-4
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