TDO2 Protein (His tag)
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- 抗原 See all TDO2 蛋白
- TDO2 (Tryptophan 2,3-Dioxygenase (TDO2))
- 蛋白类型
- Recombinant
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宿主
- Anopheles gambiae
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资源
- 合成
- 标记
- This TDO2 protein is labelled with His tag.
- 原理
- TDO (Anopheles gambiae) (rec.) (His)
- 产品特性
- Full-length TDO (Anopheles gambiae) is fused at the N-terminus to a His-tag.
- 纯度
- >98 % (SDS-PAGE)
- Biological Activity Comment
- Specific activity towards L-Trp: 87.0μmol/hr per mg. TDO catalyzes the oxidative opening of the L-tryptophan indole moiety to yield N-formylkynurenine (NFK).
- Top Product
- Discover our top product TDO2 蛋白
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Tryptophan 2,3-Dioxygenase (TDO2) (AA 307-405) protein (GST tag)
TDO2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Tryptophan 2,3-Dioxygenase (TDO2) (AA 1-406) protein (GST tag)TDO2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Tryptophan 2,3-Dioxygenase (TDO2) (Active) protein (Myc-DYKDDDDK Tag)TDO2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD Active
Tryptophan 2,3-Dioxygenase (TDO2) (AA 1-406), (full length) protein (His-SUMO Tag)TDO2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 溶解方式
- 0.5 mg/mL (Lot specific)
- 浓度
- Lot specific
- 缓冲液
- In 50 mM sodium phosphate pH 8.0, containing 0.15M sodium chloride, 0.2M imidazole and 10 % glycerol.
- 注意事项
- After opening, prepare aliquots and store at -80 °C.Avoid freeze/thaw cycles.
- 储存条件
- -20 °C,-80 °C
- 储存方法
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Short Term Storage: -20°C
Long Term Storage: -80°C
Use & Stability: Stable for at least 6 months after receipt when stored at -80°C.
- 有效期
- 6 months
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- 抗原
- TDO2 (Tryptophan 2,3-Dioxygenase (TDO2))
- 别名
- TDO (TDO2 产品)
- 背景
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TPH2, TRPO, Tryptophan 2,3-dioxygenase, Tryptophan Oxygenase, Tryptophan Pyrrolase, Tryptophanase
Tryptophan 2,3-dioxygenase (TDO) is a heme-containing dioxygenase catalyzing the addition of molecular oxygen across the 2,3-double bond of the indole ring of tryptophan to form N-formylkynurenine (NFK). In Anopheles gambiae, TDO is the only enzyme able to catalyze the first and rate-limiting step in L-Trp catabolism through the kynurenine pathway. Tryptophan is an essential amino acid for protein synthesis and also the precursor for production of a number of neurotransmitters, such as serotonin and melatonin, in mosquitoes, the kynurenine pathway is essential for eye pigmentation. Conceivably, the tryptophan-using pathways should be regulated in a coordinated manner in mosquitoes as well as in other species and TDO activation/inactivation processes could play an essential role in these phenomena.
- 分子量
- ~47.9kDa
- UniProt
- O77457
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