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PLGF 蛋白

This Recombinant PLGF protein is expressed in Insect cells (Sf9).
产品编号 ABIN2745802
发货至: 中国

Quick Overview for PLGF 蛋白 (ABIN2745802)

抗原

See all PLGF (PGF) 蛋白
PLGF (PGF) (Placenta Growth Factor (PGF))

蛋白类型

Recombinant

生物活性

Active

宿主

  • 19
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  • 1

资源

  • 14
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Insect cells (Sf9)

应用范围

SDS-PAGE (SDS)

纯度

>95 % (SDS-PAGE)
  • 原理

    PLGF (human) (rec.)

    交叉反应

    产品特性

    Human PLGF (131aa).

    Biological Activity Comment

    Measured by its ability to bind to immobilized rhsFlt-1 in a functional ELISA. Recombinant human PLGF can bind to immobilized rhsFlt-1 (100ng/well) with a linear range at 0.5-10ng/ml.
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  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstitute with 50 mM acetic acid or PBS/water. This solution can be diluted into other buffered solutions or stored frozen for future use.

    注意事项

    After reconstitution, prepare aliquots and store at -20 °C. Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution.

    储存条件

    4 °C,-20 °C

    储存方法

    Short Term Storage: +4°C

    Long Term Storage: -20°C

    Use & Stability: Stable for at least 6 months after receipt when stored at -20°C.

    有效期

    6 months
  • 抗原

    PLGF (PGF) (Placenta Growth Factor (PGF))

    别名

    PLGF

    背景

    Placenta Growth Factor, PLGF-1, PLGF-131

    Human placenta growth factor-1 (PLGF-1, PLGF) binds to the receptor FLT1/VEGFR-1. It acts as a potent chemoattractant for monocytes and only as a very weak mitogen for some endothelial cell types. The physiological function in vivo is still controversial. In several reports it was shown not to be a potent mitogen for endothelial cells and not angiogenic in vivo by using different assays. It was shown that PLGF from cell culture supernatants was angiogenic in the CAM assay and in the rabbit cornea assay.

    分子量

    ~34kDa (dimer)

    UniProt

    P49763

    途径

    VEGFR1 Specific Signals
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