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ZIC2 Protein (ZIC2) (Myc-DYKDDDDK Tag)

This Recombinant ZIC2 protein is expressed in HEK-293 Cells.
产品编号 ABIN2735883
发货至: 中国

Quick Overview for ZIC2 Protein (ZIC2) (Myc-DYKDDDDK Tag) (ABIN2735883)

抗原

See all ZIC2 蛋白
ZIC2

蛋白类型

Recombinant

宿主

资源

  • 1
  • 1
HEK-293 Cells

应用范围

Antibody Production (AbP), Standard (STD)

纯度

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • 标记

    This ZIC2 protein is labelled with Myc-DYKDDDDK Tag.

    产品特性

    • Recombinant human ZIC2 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
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    Product
    表达系统
    Conjugate
    Origin
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    表达系统 HEK-293 Cells
    Conjugate His tag
    Origin Human
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    Origin Human
    价格从 172,528.32 ¥

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  • 应用备注

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    说明

    The tag is located at the C-terminal.

    限制

    仅限研究用
  • 浓度

    50 μg/mL

    缓冲液

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

    储存条件

    -80 °C

    储存方法

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原

    ZIC2

    别名

    Zic2

    背景

    Acts as a transcriptional activator or repressor. Plays important roles in the early stage of organogenesis of the CNS. Activates the transcription of the serotonin transporter SERT in uncrossed ipsilateral retinal ganglion cells (iRGCs) to refine eye-specific projections in primary visual targets. Its transcriptional activity is repressed by MDFIC. Involved in the formation of the ipsilateral retinal projection at the optic chiasm midline. Drives the expression of EPHB1 on ipsilaterally projecting growth cones. Binds to the minimal GLI-consensus sequence 5'-TGGGTGGTC-3'. Associates to the basal SERT promoter region from ventrotemporal retinal segments of retinal embryos. [UniProtKB/Swiss-Prot Function]

    分子量

    54.8 kDa

    NCBI登录号

    NP_009060

    途径

    Tube Formation
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