WRAP53 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
Quick Overview for WRAP53 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2735538)
抗原
See all WRAP53 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- Transcript Variant 2
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标记
- This WRAP53 protein is labelled with Myc-DYKDDDDK Tag.
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产品特性
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- Recombinant human WDR79 / TCAB1 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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WD Repeat Containing, Antisense To TP53 (WRAP53) (AA 1-548) protein (His tag)
custom-made WRAP53 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
WD Repeat Containing, Antisense To TP53 (WRAP53) (AA 1-548) protein (GST tag)WRAP53 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
WD Repeat Containing, Antisense To TP53 (WRAP53) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)WRAP53 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
WD Repeat Containing, Antisense To TP53 (WRAP53) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)WRAP53 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
WD Repeat Containing, Antisense To TP53 (WRAP53) (Transcript Variant 4) protein (Myc-DYKDDDDK Tag)WRAP53 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
说明
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The tag is located at the C-terminal.
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限制
- 仅限研究用
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浓度
- 50 μg/mL
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缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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储存条件
- -80 °C
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储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- WRAP53 (WD Repeat Containing, Antisense To TP53 (WRAP53))
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别名
- Wdr79,tcab1
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背景
- This gene encodes an essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex required for telomere synthesis. This protein is enriched in Cajal bodies, nuclear sites of RNP processing that are important for telomerase function. It interacts with dyskerin, TERT and TERC, other components of active telomerase, and with small Cajal body RNAs (scaRNAs), which are involved in modifying splicing RNAs. This mRNA also functions as a p53 antisense transcript, that regulates endogenous p53 mRNA levels and further induction of p53 protein by targeting the 5' untranslated region of p53 mRNA. Alternatively spliced transcript variants which differ only in the 5' UTR have been found for this gene.
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分子量
- 59.1 kDa
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NCBI登录号
- NP_001137462
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途径
- Telomere Maintenance
抗原
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