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SNAP25 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

This Recombinant SNAP25 protein is expressed in HEK-293 Cells and has been mentioned in 4+ publications.
产品编号 ABIN2732308
发货至: 中国

Quick Overview for SNAP25 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2732308)

抗原

See all SNAP25 蛋白
SNAP25 (Synaptosomal-Associated Protein, 25kDa (SNAP25))

蛋白类型

Recombinant

宿主

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资源

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HEK-293 Cells

应用范围

Antibody Production (AbP), Standard (STD)

纯度

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • 产品特性

    Transcript Variant 1

    标记

    This SNAP25 protein is labelled with Myc-DYKDDDDK Tag.

    产品特性

    • Recombinant human SNAP25 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
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    Product
    表达系统
    Conjugate
    Origin
    价格从
    表达系统 HEK-293 Cells
    Conjugate His tag
    Origin Human
    价格从 115,504.49 ¥
    表达系统 Cell-free protein synthesis (CFPS)
    Conjugate Strep Tag
    Origin Human
    价格从 172,528.32 ¥

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  • 应用备注

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    说明

    The tag is located at the C-terminal.

    限制

    仅限研究用
  • 浓度

    50 μg/mL

    缓冲液

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

    储存条件

    -80 °C

    储存方法

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Brinkmalm, Brinkmalm, Honer, Moreno, Jakobsson, Mallucci, Zetterberg, Blennow, Öhrfelt: "Targeting synaptic pathology with a novel affinity mass spectrometry approach." in: Molecular & cellular proteomics : MCP, Vol. 13, Issue 10, pp. 2584-92, (2014) (PubMed).

    Brinkmalm, Brinkmalm, Honer, Frölich, Hausner, Minthon, Hansson, Wallin, Zetterberg, Blennow, Öhrfelt: "SNAP-25 is a promising novel cerebrospinal fluid biomarker for synapse degeneration in Alzheimer's disease." in: Molecular neurodegeneration, Vol. 9, pp. 53, (2014) (PubMed).

    Kariolis, Miao, Jones, Kapur, Mathews, Giaccia, Cochran: "An engineered Axl 'decoy receptor' effectively silences the Gas6-Axl signaling axis." in: Nature chemical biology, Vol. 10, Issue 11, pp. 977-83, (2014) (PubMed).

    Chen, Fu, Chen, Hu, Soroka, Prigge, Schmidt, Yan, Major, Chen, Sang: "Ginger compound [6]-shogaol and its cysteine-conjugated metabolite (M2) activate Nrf2 in colon epithelial cells in vitro and in vivo." in: Chemical research in toxicology, Vol. 27, Issue 9, pp. 1575-85, (2014) (PubMed).

  • 抗原

    SNAP25 (Synaptosomal-Associated Protein, 25kDa (SNAP25))

    别名

    Snap25

    背景

    Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene.

    分子量

    23.2 kDa

    NCBI登录号

    NP_003072

    途径

    Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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