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SLIT2 蛋白

SLIT2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD, Func, PI Active
产品编号 ABIN2732203
发货至: 中国
  • 抗原 See all SLIT2 蛋白
    SLIT2 (Slit Homolog 2 (Drosophila) (SLIT2))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 10
    • 5
    • 3
    资源
    • 7
    • 6
    • 3
    • 1
    • 1
    HEK-293 Cells
    应用范围
    Antibody Production (AbP), Standard (STD), Functional Studies (Func), Protein Interaction (PI)
    特异性
    Optimal preservation of protein structure, post-translational modifications and functions.
    产品特性
    • Recombinant human SLIT2 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    • Tested for bioactivity.
    纯度
    > 95 % as determined by SDS-PAGE and Coomassie blue staining
    内毒素水平
    Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
    Biological Activity Comment
    Determined by its ability to inhibit MC3T3/E1 osteoblasts cell differentiation.
    Top Product
    Discover our top product SLIT2 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Protein-protein interaction
    In vitro biochemical assays and cell-based functional assays
    限制
    仅限研究用
  • 缓冲液
    Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
    注意事项
    Resuspend the protein in the desired concentration in proper buffer
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    SLIT2 (Slit Homolog 2 (Drosophila) (SLIT2))
    别名
    Slit2 (SLIT2 产品)
    背景
    This gene encodes a member of the slit family of secreted glycoproteins, which are ligands for the Robo family of immunoglobulin receptors. Slit proteins play highly conserved roles in axon guidance and neuronal migration and may also have functions during other cell migration processes including leukocyte migration. Members of the slit family are characterized by an N-terminal signal peptide, four leucine-rich repeats, nine epidermal growth factor repeats, and a C-terminal cysteine knot. Proteolytic processing of this protein gives rise to an N-terminal fragment that contains the four leucine-rich repeats and five epidermal growth factor repeats and a C-terminal fragment that contains four epidermal growth factor repeats and the cysteine knot. Both full length and cleaved proteins are secreted extracellularly and can function in axon repulsion as well as other specific processes. Alternative splicing results in multiple transcript variants.
    分子量
    120 kDa
    NCBI登录号
    NP_004778
    途径
    Regulation of Actin Filament Polymerization, Regulation of Cell Size, Smooth Muscle Cell Migration
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