SAA1 Protein (Transcript Variant 1)
This Recombinant SAA1 protein is expressed in 大肠杆菌（E. Coli）.
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产品编号 ABIN2731847
发货至:
中国
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中国
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北京 101111
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Quick Overview for SAA1 Protein (Transcript Variant 1) (ABIN2731847)
抗原
See all SAA1 蛋白
SAA1
(Serum Amyloid A1 (SAA1))
蛋白类型
Recombinant
生物活性
Active
宿主
人
资源
大肠杆菌（E. Coli）
应用范围
Functional Studies (Func), Antibody Production (AbP), Standard (STD), Protein Interaction (PI)
纯度
> 95 % as determined by SDS-PAGE and Coomassie blue staining
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产品特性
- Transcript Variant 1
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特异性
- Optimal preservation of protein structure, post-translational modifications and functions.
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产品特性
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- Recombinant human Serum amyloid A1 (SAA1), transcript variant 1. (transcript variant 1) protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Tested for bioactivity.
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内毒素水平
- Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
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Biological Activity Comment
- Tested by its ability to down-regulate lipid biosynthesis in aortic smooth muscle cells. The effective concentration was found to be 4 uM.* * Schreiber, BM. et al. Biochem J. 1999 Nov 15 344 Pt 1:7-13
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Serum Amyloid A1 (SAA1) (AA 18-122) protein (His tag)
SAA1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB
Serum Amyloid A1 (SAA1) (AA 1-122) protein (GST tag)SAA1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
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应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays -
限制
- 仅限研究用
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缓冲液
- Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
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注意事项
- Resuspend the protein in the desired concentration in proper buffer
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储存条件
- -80 °C
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储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- SAA1 (Serum Amyloid A1 (SAA1))
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背景
- This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Alternate splicing results in multiple transcript variants that encode the same protein. A pseudogene of this gene is found on chromosome 11.
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分子量
- 12 kDa
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NCBI登录号
- NP_000322
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途径
- Toll-Like Receptors Cascades
抗原
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