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PAK7 Protein (Transcript Variant 2)

This Recombinant PAK7 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN2728183
发货至: 中国

Quick Overview for PAK7 Protein (Transcript Variant 2) (ABIN2728183)

抗原

See all PAK7 蛋白
PAK7 (P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7))

蛋白类型

Recombinant

生物活性

Active

宿主

  • 4
  • 2
  • 1

资源

  • 3
  • 2
  • 1
  • 1
大肠杆菌(E. Coli)

应用范围

Antibody Production (AbP), Standard (STD), Functional Studies (Func), Protein Interaction (PI)

纯度

> 90 % as determined by SDS-PAGE and Coomassie blue staining
  • 产品特性

    Transcript Variant 2

    特异性

    Optimal preservation of protein structure, post-translational modifications and functions.

    产品特性

    • Recombinant human PAK7 / PAK5 (transcript variant 2) protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
    • Tested for bioactivity.

    内毒素水平

    <0.1 ng/μg of protein (<1EU/μg).

    Biological Activity Comment

    Specific activity was determined as 4,199 pmoles/min/μg, according to the Zlyte assay protocol
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  • 应用备注

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Protein-protein interaction
    In vitro biochemical assays and cell-based functional assays

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    25 mM Tris-HCl pH 8.0, 150 mM NaCl, 10 % glycerol, 5 mM DTT.

    储存条件

    -80 °C

    储存方法

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原

    PAK7 (P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7))

    别名

    Pak7,pak5

    背景

    The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described.

    分子量

    33.9 kda

    NCBI登录号

    NP_817127
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