LMOD3 Protein (Myc-DYKDDDDK Tag)
Quick Overview for LMOD3 Protein (Myc-DYKDDDDK Tag) (ABIN2724614)
抗原
蛋白类型
宿主
资源
应用范围
纯度
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标记
- This LMOD3 protein is labelled with Myc-DYKDDDDK Tag.
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产品特性
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- Recombinant human Leiomodin-3 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Leiomodin 3 (LMOD3) (AA 1-560) protein (His tag)
custom-made LMOD3 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Leiomodin 3 (LMOD3) (AA 1-236) protein (GST tag)LMOD3 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
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应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
说明
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The tag is located at the C-terminal.
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限制
- 仅限研究用
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浓度
- 50 μg/mL
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缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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储存条件
- -80 °C
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储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- LMOD3 (Leiomodin 3 (LMOD3))
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别名
- Leiomodin-3
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背景
- The protein encoded by this gene is a member of the leiomodin family of proteins. This protein contains three actin-binding domains, a tropomyosin domain, a leucine-rich repeat domain, and a Wiskott-Aldrich syndrome protein homology 2 domain (WH2). Localization of this protein to the pointed ends of thin filaments has been observed, and there is evidence that this protein acts as a catalyst of actin nucleation, and is important to the organization of sarcomeric thin filaments in skeletal muscles. Mutations in this gene have been associated as one cause of Nemaline myopathy, as other genes have also been linked to this disorder. Nemaline myopathy is a disorder characterized by nonprogressive generalized muscle weakness and protein inclusions (nemaline bodies) in skeletal myofibers. Patients with mutations in this gene often present with a severe congenital form of the disorder.
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分子量
- 64.7 kDa
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NCBI登录号
- NP_938012
抗原
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