KIAA0562 Protein (KIAA0562) (Myc-DYKDDDDK Tag)
This Recombinant KIAA0562 protein is expressed in HEK-293 Cells.
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产品编号 ABIN2724200
发货至:
中国
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Quick Overview for KIAA0562 Protein (KIAA0562) (Myc-DYKDDDDK Tag) (ABIN2724200)
抗原
KIAA0562
蛋白类型
Recombinant
宿主
人
资源
HEK-293 Cells
应用范围
Antibody Production (AbP), Standard (STD)
纯度
> 80 % as determined by SDS-PAGE and Coomassie blue staining
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标记
- This KIAA0562 protein is labelled with Myc-DYKDDDDK Tag.
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产品特性
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- Recombinant human KIAA0562 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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KIAA0562 (KIAA0562) (AA 1-554) protein (GST tag)
KIAA0562 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
KIAA0562 (KIAA0562) (AA 29-181) protein (His-IF2DI Tag)KIAA0562 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB
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应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
说明
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The tag is located at the C-terminal.
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限制
- 仅限研究用
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浓度
- 50 μg/mL
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缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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储存条件
- -80 °C
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储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- KIAA0562
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别名
- Kiaa0562
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背景
- This gene encodes a centrosomal protein required for ciliogenesis and for ciliary tip structural integrity. The mammalian protein contains three amino-terminal hydrophobic domains, two glycosylation sites, four cysteine-rich motifs, and two regions with homology to the glutamate receptor ionotropic, NMDA 1 protein. During ciliogenesis, the encoded protein translocates from the distal tips of the centrioles to the tip of the elongating cilium. Knockdown of the protein in human retinal pigment cells results in severe defects in ciliogenesis with structural deformities at the ciliary tips. Allelic variants of this gene are associated with the autosomal-recessive disorder Joubert syndrome, which is characterized by a distinctive mid-hindbrain and cerebellar malformation, oculomotor apraxia, irregular breathing, developmental delay, and ataxia.
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分子量
- 104.3 kDa
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NCBI登录号
- NP_055519
抗原
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