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IL16 Protein (Transcript Variant 3)

This Recombinant IL16 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN2723625
发货至: 中国

Quick Overview for IL16 Protein (Transcript Variant 3) (ABIN2723625)

抗原

See all IL16 蛋白
IL16 (Interleukin 16 (IL16))

蛋白类型

Recombinant

生物活性

Active

宿主

  • 16
  • 9
  • 2
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  • 1
  • 1

资源

  • 27
  • 3
  • 2
  • 1
大肠杆菌(E. Coli)

应用范围

Functional Studies (Func), Antibody Production (AbP), Standard (STD), Protein Interaction (PI)

纯度

> 95 % as determined by SDS-PAGE and Coomassie blue staining
  • 产品特性

    Transcript Variant 3

    特异性

    Optimal preservation of protein structure, post-translational modifications and functions.

    产品特性

    • Recombinant human Interleukin-16 / IL16 (transcript variant 3) protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
    • Tested for bioactivity.

    内毒素水平

    < 0.1 EU per μg protein as determined by LAL test

    Biological Activity Comment

    Specific Activity is greater than 1.0 x 104 IU/mg as determined by the ability of Recombinant IL-16 to chemoattract human CD4+ T lymphocytes using a concentration range of 10.0-100.0 ng/ml
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  • 应用备注

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Protein-protein interaction
    In vitro biochemical assays and cell-based functional assays

    限制

    仅限研究用
  • 缓冲液

    Lyophilized from a 0.2 μM filtered solution of 20 mM Phosphate buffer, 150 mM NaCl, pH 7.0. Stable for at least 6 months from date of receipt under proper storage and handling conditions.

    储存条件

    -80 °C

    储存方法

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原

    IL16 (Interleukin 16 (IL16))

    别名

    Interleukin-16,il16

    背景

    Isoform 3 is involved in cell cycle progression in T-cells. Appears to be involved in transcriptional regulation of SKP2 and is probably part of a transcriptional repression complex on the core promoter of the SKP2 gene. May act as a scaffold for GABPB1 (the DNA-binding subunit the GABP transcription factor complex) and HDAC3 thus maintaining transcriptional repression and blocking cell cycle progression in resting T-cells. [UniProtKB/Swiss-Prot Function]

    分子量

    13.3 kDa

    NCBI登录号

    NP_001165599
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