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IL-13 Protein (DYKDDDDK-His Tag)

This Recombinant IL-13 protein is expressed in HEK-293 Cells.
产品编号 ABIN2723606
发货至: 中国

Quick Overview for IL-13 Protein (DYKDDDDK-His Tag) (ABIN2723606)

抗原

See all IL-13 (IL13) 蛋白
IL-13 (IL13) (Interleukin 13 (IL13))

蛋白类型

Recombinant

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资源

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HEK-293 Cells

应用范围

Antibody Production (AbP), Standard (STD)

纯度

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • 标记

    This IL-13 protein is labelled with DYKDDDDK-His Tag.

    产品特性

    • Recombinant human Interleukin-13 / IL13 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
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  • 应用备注

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    说明

    The tag is located at the N-terminal.

    限制

    仅限研究用
  • 浓度

    50 μg/mL

    缓冲液

    1 x PBS, pH 7.4. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.

    储存条件

    -80 °C

    储存方法

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原

    IL-13 (IL13) (Interleukin 13 (IL13))

    别名

    Interleukin-13,il13

    背景

    This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4.

    分子量

    16 kDa

    NCBI登录号

    NP_002179

    途径

    JAK/STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport
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