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IL12A 蛋白

IL12A 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2723596
发货至: 中国
  • 抗原 See all IL12A 蛋白
    IL12A (Interleukin 12 alpha (IL12A))
    蛋白类型
    Recombinant
    宿主
    • 7
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    资源
    • 15
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    HEK-293 Cells
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human Interleukin-12 alpha / IL12A protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 95 % as determined by SDS-PAGE and Coomassie blue staining
    内毒素水平
    Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
    Top Product
    Discover our top product IL12A 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    限制
    仅限研究用
  • 缓冲液
    Lyophilized from a 0.2 μM filtered solution of PBS, pH 7.4
    注意事项
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    IL12A (Interleukin 12 alpha (IL12A))
    别名
    Interleukin-12 Alpha,il12a (IL12A 产品)
    别名
    CLMF Protein, IL-12A Protein, NFSK Protein, NKSF1 Protein, P35 Protein, CLMF2 Protein, IL-12B Protein, NKSF Protein, NKSF2 Protein, p40 Protein, Il-12b Protein, Il12p40 Protein, Il-12p40 Protein, Il12 Protein, IL-12p40 Protein, IL-12p35 Protein, Il-12a Protein, Ll12a Protein, p35 Protein, IL12p35 Protein, Il-12 p35 Protein, IL12p40 Protein, IL12 Protein, IL-12 p35 Protein, interleukin 12A Protein, interleukin 12B Protein, interleukin 12b Protein, interleukin 12a Protein, Interleukin 12 level Protein, IL12A Protein, IL12B Protein, Il12b Protein, Il12a Protein, IL12 Protein, il12a Protein
    背景
    This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity.
    分子量
    57.2kD
    NCBI登录号
    NP_000873
    途径
    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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