ITGA8 Protein (Myc-DYKDDDDK Tag)
This Recombinant ITGA8 protein is expressed in HEK-293 Cells.
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Quick Overview for ITGA8 Protein (Myc-DYKDDDDK Tag) (ABIN2723529)
抗原
See all ITGA8 蛋白
ITGA8
(Integrin alpha-8 (ITGA8))
蛋白类型
Recombinant
宿主
人
资源
HEK-293 Cells
应用范围
Antibody Production (AbP), Standard (STD)
纯度
> 80 % as determined by SDS-PAGE and Coomassie blue staining
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标记
- This ITGA8 protein is labelled with Myc-DYKDDDDK Tag.
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产品特性
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- Recombinant human Integrin alpha-8 / ITGA8 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Integrin alpha-8 (ITGA8) (AA 836-935) protein (GST tag)
ITGA8 宿主: 人 宿主: 小麦胚 Recombinant WB, AP, AA, ELISA
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应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
说明
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The tag is located at the C-terminal.
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限制
- 仅限研究用
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浓度
- 50 μg/mL
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缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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储存条件
- -80 °C
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储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- ITGA8 (Integrin alpha-8 (ITGA8))
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别名
- Integrin alpha-8,itga8
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背景
- Integrins are heterodimeric transmembrane receptor proteins that mediate numerous cellular processes including cell adhesion, cytoskeletal rearrangement, and activation of cell signaling pathways. Integrins are composed of alpha and beta subunits. This gene encodes the alpha 8 subunit of the heterodimeric integrin alpha8beta1 protein. The encoded protein is a single-pass type 1 membrane protein that contains multiple FG-GAP repeats. This repeat is predicted to fold into a beta propeller structure. This gene regulates the recruitment of mesenchymal cells into epithelial structures, mediates cell-cell interactions, and regulates neurite outgrowth of sensory and motor neurons. The integrin alpha8beta1 protein thus plays an important role in wound-healing and organogenesis. Mutations in this gene have been associated with renal hypodysplasia/aplasia-1 (RHDA1) and with several animal models of chronic kidney disease. Alternate splicing results in multiple transcript variants encoding distinct isoforms.
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分子量
- 117.3 kDa
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NCBI登录号
- NP_003629
抗原
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