HAX1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
Quick Overview for HAX1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2722446)
抗原
See all HAX1 蛋白蛋白类型
宿主
资源
应用范围
纯度
-
-
产品特性
- Transcript Variant 1
-
标记
- This HAX1 protein is labelled with Myc-DYKDDDDK Tag.
-
产品特性
-
- Recombinant human HAX1 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
-
-
-
-
应用备注
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
说明
-
The tag is located at the C-terminal.
-
限制
- 仅限研究用
-
-
-
浓度
- 50 μg/mL
-
缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
-
储存条件
- -80 °C
-
储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
-
- HAX1 (HCLS1 Associated Protein X-1 (HAX1))
-
别名
- Hax1
-
背景
- The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene.
-
分子量
- 31.4 kDa
-
NCBI登录号
- NP_006109
-
途径
- Regulation of Actin Filament Polymerization
抗原
-