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E2F5 Protein (E2F5) (His tag)

This Recombinant E2F5 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN2719897
发货至: 中国

Quick Overview for E2F5 Protein (E2F5) (His tag) (ABIN2719897)

抗原

See all E2F5 蛋白
E2F5

蛋白类型

Recombinant

宿主

  • 4
  • 2

资源

  • 3
  • 2
  • 1
大肠杆菌(E. Coli)

应用范围

Antibody Production (AbP), Standard (STD)

纯度

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • 标记

    This E2F5 protein is labelled with His tag.

    产品特性

    • Recombinant human E2F5 (N-term HIS tag, transcript variant 1) protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
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    Product
    表达系统
    Conjugate
    Origin
    价格从
    表达系统 HEK-293 Cells
    Conjugate His tag
    Origin Human
    价格从 115,504.49 ¥
    表达系统 Cell-free protein synthesis (CFPS)
    Conjugate Strep Tag
    Origin Human
    价格从 152,621.24 ¥

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  • 应用备注

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    说明

    The tag is located at the N-terminal.

    限制

    仅限研究用
  • 浓度

    50 μg/mL

    缓冲液

    25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.

    储存条件

    -80 °C

    储存方法

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原

    E2F5

    别名

    e2f5

    背景

    The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionarily conserved domains that are present in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein is differentially phosphorylated and is expressed in a wide variety of human tissues. It has higher identity to E2F4 than to other family members. Both this protein and E2F4 interact with tumor suppressor proteins p130 and p107, but not with pRB. Alternative splicing results in multiple variants encoding different isoforms.

    分子量

    37.4 kDa

    NCBI登录号

    NP_001942
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