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Dystrophin Protein (DMD) (Myc-DYKDDDDK Tag)

This Recombinant Dystrophin protein is expressed in HEK-293 Cells.
产品编号 ABIN2719890
发货至: 中国

Quick Overview for Dystrophin Protein (DMD) (Myc-DYKDDDDK Tag) (ABIN2719890)

抗原

See all Dystrophin (DMD) 蛋白
Dystrophin (DMD)

蛋白类型

Recombinant

宿主

  • 4
  • 2

资源

  • 5
  • 1
HEK-293 Cells

应用范围

Antibody Production (AbP), Standard (STD)

纯度

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • 标记

    This Dystrophin protein is labelled with Myc-DYKDDDDK Tag.

    产品特性

    • Recombinant human Dystrophin / DMD (transcript variant Dp140b) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
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  • 应用备注

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    说明

    The tag is located at the C-terminal.

    限制

    仅限研究用
  • 浓度

    50 μg/mL

    缓冲液

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

    储存条件

    -80 °C

    储存方法

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原

    Dystrophin (DMD)

    别名

    Dystrophin,dmd

    背景

    This gene spans a genomic range of greater than 2 Mb and encodes a large protein containing an N-terminal actin-binding domain and multiple spectrin repeats. The encoded protein forms a component of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extracellular matrix. Deletions, duplications, and point mutations at this gene locus may cause Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), or cardiomyopathy. Alternative promoter usage and alternative splicing result in numerous distinct transcript variants and protein isoforms for this gene.

    分子量

    143 kDa

    NCBI登录号

    NP_004012

    途径

    Skeletal Muscle Fiber Development
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