Dystrophin Protein (DMD) (Myc-DYKDDDDK Tag)
Quick Overview for Dystrophin Protein (DMD) (Myc-DYKDDDDK Tag) (ABIN2719890)
抗原
See all Dystrophin (DMD) 蛋白蛋白类型
宿主
资源
应用范围
纯度
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标记
- This Dystrophin protein is labelled with Myc-DYKDDDDK Tag.
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产品特性
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- Recombinant human Dystrophin / DMD (transcript variant Dp140b) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
说明
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The tag is located at the C-terminal.
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限制
- 仅限研究用
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浓度
- 50 μg/mL
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缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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储存条件
- -80 °C
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储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Dystrophin (DMD)
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别名
- Dystrophin,dmd
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背景
- This gene spans a genomic range of greater than 2 Mb and encodes a large protein containing an N-terminal actin-binding domain and multiple spectrin repeats. The encoded protein forms a component of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extracellular matrix. Deletions, duplications, and point mutations at this gene locus may cause Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), or cardiomyopathy. Alternative promoter usage and alternative splicing result in numerous distinct transcript variants and protein isoforms for this gene.
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分子量
- 143 kDa
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NCBI登录号
- NP_004012
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途径
- Skeletal Muscle Fiber Development
抗原
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