BMP10 蛋白
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- 抗原 See all BMP10 蛋白
- BMP10 (Bone Morphogenetic Protein 10 (BMP10))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- HEK-293 Cells
- 应用范围
- Antibody Production (AbP), Functional Studies (Func), Protein Interaction (PI), Standard (STD)
- 特异性
- Optimal preservation of protein structure, post-translational modifications and functions.
- 产品特性
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- Recombinant human BMP10 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Tested for bioactivity.
- 纯度
- > 95 % as determined by SDS-PAGE and Coomassie blue staining
- 内毒素水平
- Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
- Biological Activity Comment
- Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 4.0-6.0 ng/ml.
- Top Product
- Discover our top product BMP10 蛋白
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Bone Morphogenetic Protein 10 (BMP10) (AA 1-424) protein (GST tag)
BMP10 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Bone Morphogenetic Protein 10 (BMP10) (AA 317-424) protein (GST tag)BMP10 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Bone Morphogenetic Protein 10 (BMP10) (AA 317-424) protein (His tag)Crystallography grade BMP10 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Bone Morphogenetic Protein 10 (BMP10) (AA 314-421) protein (His tag)Crystallography grade BMP10 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Bone Morphogenetic Protein 10 (BMP10) proteinBMP10 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % WB, SDS, ELISA, IP
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays - 限制
- 仅限研究用
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- 缓冲液
- Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
- 注意事项
- Resuspend the protein in the desired concentration in proper buffer
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- BMP10 (Bone Morphogenetic Protein 10 (BMP10))
- 别名
- Bmp10 (BMP10 产品)
- 别名
- BMP10 Protein, si:dkey-13n15.5 Protein, Bmp10 Protein, BMP9 Protein, BMP-10 Protein, bone morphogenetic protein 10 Protein, BMP10 Protein, bmp10 Protein, LOC662386 Protein, Bmp10 Protein
- 背景
- This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which binds to the activin receptor-like kinase 1 (ALK1) and plays important roles in cardiovascular development including cardiomyocyte proliferation and regulation of heart size, closure of the ductus arteriosus, angiogenesis and ventricular trabeculation.
- 分子量
- 24.4 kDa
- NCBI登录号
- NP_055297
- 途径
- Hormone Activity, Regulation of Muscle Cell Differentiation
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