BCL2A1 Protein (Transcript Variant 2)
Quick Overview for BCL2A1 Protein (Transcript Variant 2) (ABIN2715200)
抗原
See all BCL2A1 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- Transcript Variant 2
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产品特性
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- Recombinant human Bcl-2-like 5 (transcript variant 2) protein expressed in E. coli.
- Produced with end-sequenced ORF clone
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内毒素水平
- < 0.1 EU per μg protein as determined by LAL test
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应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
限制
- 仅限研究用
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浓度
- 50 μg/mL
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缓冲液
- 20 mM Phosphate buffer, 150 mM NaCl, 1 mM EDTA, 1 mM DTT, 10 % Glycerol, pH 7.4. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
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储存条件
- -80 °C
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储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- BCL2A1 (BCL2-Related Protein A1 (BCL2A1))
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别名
- Bcl-2-Like 5
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背景
- This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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分子量
- 18.5 kDa
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NCBI登录号
- NP_001108207
抗原
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