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APOE Protein (Myc-DYKDDDDK Tag)

This Recombinant APOE protein is expressed in HEK-293 Cells and has been mentioned in 1 publication.
产品编号 ABIN2714829
发货至: 中国

Quick Overview for APOE Protein (Myc-DYKDDDDK Tag) (ABIN2714829)

抗原

See all APOE 蛋白
APOE (Apolipoprotein E (APOE))

蛋白类型

Recombinant

宿主

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资源

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HEK-293 Cells

应用范围

Antibody Production (AbP), Standard (STD)

纯度

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • 标记

    This APOE protein is labelled with Myc-DYKDDDDK Tag.

    产品特性

    • Recombinant human Apolipoprotein E / Apo E protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
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  • 应用备注

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    说明

    The tag is located at the C-terminal.

    限制

    仅限研究用
  • 浓度

    50 μg/mL

    缓冲液

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

    储存条件

    -80 °C

    储存方法

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Pan, Zhou, Mahsut, Rohm, Berejnaia, Price, Chen, Castro-Perez, Lassman, McLaren, Conway, Jensen, Thomas, Reyes-Soffer, Ginsberg, Gutstein, Cleary, Previs, Roddy: "Static and turnover kinetic measurement of protein biomarkers involved in triglyceride metabolism including apoB48 and apoA5 by LC/MS/MS." in: Journal of lipid research, Vol. 55, Issue 6, pp. 1179-87, (2016) (PubMed).

  • 抗原

    APOE (Apolipoprotein E (APOE))

    别名

    Apolipoprotein E,apo E

    背景

    The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.

    分子量

    34.2 kDa

    NCBI登录号

    NP_000032

    途径

    Regulation of Cell Size, Lipid Metabolism
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