A2ML1 Protein (Myc-DYKDDDDK Tag)
This Recombinant A2ML1 protein is expressed in HEK-293 Cells.
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Quick Overview for A2ML1 Protein (Myc-DYKDDDDK Tag) (ABIN2714611)
抗原
See all A2ML1 蛋白
A2ML1
(alpha-2-Macroglobulin-Like 1 (A2ML1))
蛋白类型
Recombinant
宿主
人
资源
HEK-293 Cells
应用范围
Antibody Production (AbP), Standard (STD)
纯度
> 80 % as determined by SDS-PAGE and Coomassie blue staining
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标记
- This A2ML1 protein is labelled with Myc-DYKDDDDK Tag.
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产品特性
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- Recombinant human Alpha-2-macroglobulin-like 1 (A2ML1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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alpha-2-Macroglobulin-Like 1 (A2ML1) (AA 1-158) protein (GST tag)
A2ML1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
alpha-2-Macroglobulin-Like 1 (A2ML1) proteinA2ML1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % WB, SDS, ELISA, IP
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应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
说明
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The tag is located at the C-terminal.
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限制
- 仅限研究用
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浓度
- 50 μg/mL
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缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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储存条件
- -80 °C
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储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- A2ML1 (alpha-2-Macroglobulin-Like 1 (A2ML1))
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背景
- This gene encodes a member of the alpha-macroglobulin superfamily. The encoded protein is thought to be an N-glycosylated monomeric protein that acts as an inhibitor of several proteases. It has been shown to form covalent interactions with proteases, and has been reported as the p170 antigen recognized by autoantibodies in the autoimmune disease paraneoplastic pemphigus (PNP PMID:20805888). Mutations in these gene have also been associated with some cases of Noonan syndrome (NS PMID:24939586) as well as some cases of otitis media (PMID:26121085). Alternative splicing results in multiple transcript variants encoding different isoforms.
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分子量
- 161 kDa
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NCBI登录号
- NP_653271
抗原
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