Aconitase 1 Protein (ACO1) (Myc-DYKDDDDK Tag)
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- 抗原 See all Aconitase 1 (ACO1) 蛋白
- Aconitase 1 (ACO1)
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This Aconitase 1 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human ACO1 / IREB1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product ACO1 蛋白
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Aconitase 1 (ACO1) (AA 1-889) protein (GST tag)
ACO1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Aconitase 1 (ACO1) (AA 780-889) protein (GST tag)ACO1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Aconitase 1 (ACO1) (AA 1-889) protein (His tag)ACO1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % by SDS - PAGE SDS
Aconitase 1 (ACO1) (AA 1-889) protein (Strep Tag)Crystallography grade ACO1 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Aconitase 1 (ACO1) (AA 1-889) protein (Strep Tag)Crystallography grade ACO1 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- Aconitase 1 (ACO1)
- 别名
- Aco1,ireb1 (ACO1 产品)
- 别名
- ACONS Protein, IREB1 Protein, IREBP Protein, IREBP1 Protein, IRP1 Protein, Acon1 Protein, Ratireb Protein, ratireb Protein, Aco1 Protein, AI256519 Protein, Aco-1 Protein, Irebp Protein, Irp1 Protein, aconitase 1 Protein, aconitase 1, soluble Protein, aconitase 1 L homeolog Protein, ACO1 Protein, Aco1 Protein, aco1.L Protein
- 背景
- The protein encoded by this gene is a bifunctional, cytosolic protein that functions as an essential enzyme in the TCA cycle and interacts with mRNA to control the levels of iron inside cells. When cellular iron levels are high, this protein binds to a 4Fe-4S cluster and functions as an aconitase. Aconitases are iron-sulfur proteins that function to catalyze the conversion of citrate to isocitrate. When cellular iron levels are low, the protein binds to iron-responsive elements (IREs), which are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor mRNA. When the protein binds to IRE, it results in repression of translation of ferritin mRNA, and inhibition of degradation of the otherwise rapidly degraded transferrin receptor mRNA. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Alternative splicing results in multiple transcript variants
- 分子量
- 98.2 kDa
- NCBI登录号
- NP_002188
- 途径
- Transition Metal Ion Homeostasis
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