Aconitase 1 Protein (ACO1) (Myc-DYKDDDDK Tag)
Quick Overview for Aconitase 1 Protein (ACO1) (Myc-DYKDDDDK Tag) (ABIN2714323)
抗原
See all Aconitase 1 (ACO1) 蛋白蛋白类型
宿主
资源
应用范围
纯度
-
-
标记
- This Aconitase 1 protein is labelled with Myc-DYKDDDDK Tag.
-
产品特性
-
- Recombinant human ACO1 / IREB1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
-
-
想要此Protein的其他选项吗？
!探索我们的预定义定制蛋白和定制蛋白服务！Product表达系统ConjugateOrigin价格从表达系统 HEK-293 CellsConjugate His tagOrigin Human价格从 106,314.67 ¥表达系统 Cell-free protein synthesis (CFPS)Conjugate Strep TagOrigin Human价格从 172,528.32 ¥您的项目需要进一步定制吗？联系我们，了解我们的定制蛋白解决方案
-
Aconitase 1 (ACO1) (AA 1-889) protein (His tag)
custom-made ACO1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Aconitase 1 (ACO1) (AA 1-889) protein (His tag)custom-made ACO1 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Aconitase 1 (ACO1) (AA 780-889) protein (GST tag)ACO1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Aconitase 1 (ACO1) (AA 1-889) protein (GST tag)ACO1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Aconitase 1 (ACO1) (AA 1-889) protein (His tag)ACO1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % by SDS - PAGE SDS
-
-
应用备注
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
说明
-
The tag is located at the C-terminal.
-
限制
- 仅限研究用
-
-
-
浓度
- 50 μg/mL
-
缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
-
储存条件
- -80 °C
-
储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
-
- Aconitase 1 (ACO1)
-
别名
- Aco1,ireb1
-
背景
- The protein encoded by this gene is a bifunctional, cytosolic protein that functions as an essential enzyme in the TCA cycle and interacts with mRNA to control the levels of iron inside cells. When cellular iron levels are high, this protein binds to a 4Fe-4S cluster and functions as an aconitase. Aconitases are iron-sulfur proteins that function to catalyze the conversion of citrate to isocitrate. When cellular iron levels are low, the protein binds to iron-responsive elements (IREs), which are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor mRNA. When the protein binds to IRE, it results in repression of translation of ferritin mRNA, and inhibition of degradation of the otherwise rapidly degraded transferrin receptor mRNA. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Alternative splicing results in multiple transcript variants
-
分子量
- 98.2 kDa
-
NCBI登录号
- NP_002188
-
途径
- Transition Metal Ion Homeostasis
抗原
-
