ASAH1 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- 抗原 See all ASAH1 蛋白
- ASAH1 (N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1))
- 蛋白类型
- Recombinant
- 产品特性
- Transcript Variant 2
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This ASAH1 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human Acid ceramidase (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product ASAH1 蛋白
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- ASAH1 (N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1))
- 别名
- Acid Ceramidase (ASAH1 产品)
- 别名
- AC Protein, ACDase Protein, ASAH Protein, PHP Protein, PHP32 Protein, SMAPME Protein, 2310081N20Rik Protein, Asah Protein, MGC82286 Protein, asah1 Protein, zgc:101637 Protein, ASAH1 Protein, zgc:66026 Protein, N-acylsphingosine amidohydrolase 1 Protein, N-acylsphingosine amidohydrolase (acid ceramidase) 1 Protein, N-acylsphingosine amidohydrolase (acid ceramidase) 1 L homeolog Protein, N-acylsphingosine amidohydrolase (acid ceramidase) 1a Protein, Acid ceramidase Protein, N-acylsphingosine amidohydrolase (acid ceramidase) 1b Protein, ASAH1 Protein, Asah1 Protein, asah1.L Protein, asah1a Protein, asah-1 Protein, asah1b Protein
- 背景
- This gene encodes a member of the acid ceramidase family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. Processing of this preproprotein generates alpha and beta subunits that heterodimerize to form the mature lysosomal enzyme, which catalyzes the degradation of ceramide into sphingosine and free fatty acid. This enzyme is overexpressed in multiple human cancers and may play a role in cancer progression. Mutations in this gene are associated with the lysosomal storage disorder, Farber lipogranulomatosis, and a neuromuscular disorder, spinal muscular atrophy with progressive myoclonic epilepsy.
- 分子量
- 46.3 kDa
- NCBI登录号
- NP_004306
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