ASAH1 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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Quick Overview for ASAH1 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2714319)
抗原
See all ASAH1 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- Transcript Variant 2
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标记
- This ASAH1 protein is labelled with Myc-DYKDDDDK Tag.
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产品特性
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- Recombinant human Acid ceramidase (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1) (AA 1-395) protein (GST tag)
ASAH1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1) (AA 22-395) protein (His-IF2DI Tag)ASAH1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1) (AA 25-124) protein (GST tag)ASAH1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
说明
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The tag is located at the C-terminal.
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限制
- 仅限研究用
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浓度
- 50 μg/mL
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缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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储存条件
- -80 °C
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储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- ASAH1 (N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1))
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别名
- Acid Ceramidase
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背景
- This gene encodes a member of the acid ceramidase family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. Processing of this preproprotein generates alpha and beta subunits that heterodimerize to form the mature lysosomal enzyme, which catalyzes the degradation of ceramide into sphingosine and free fatty acid. This enzyme is overexpressed in multiple human cancers and may play a role in cancer progression. Mutations in this gene are associated with the lysosomal storage disorder, Farber lipogranulomatosis, and a neuromuscular disorder, spinal muscular atrophy with progressive myoclonic epilepsy.
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分子量
- 46.3 kDa
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NCBI登录号
- NP_004306
抗原
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