PDGFRB 蛋白
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- 抗原 See all PDGFRB 蛋白
- PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 应用范围
- Antibody Production (AbP), Standard (STD), Functional Studies (Func), Protein Interaction (PI)
- 特异性
- Optimal preservation of protein structure, post-translational modifications and functions.
- 产品特性
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- Recombinant human CD140b / PDGFRB protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Tested for bioactivity.
- 纯度
- > 98 % , as determined by Coomassie stained SDS-PAGE.
- 内毒素水平
- Less than 0.01 ng per μg protein as determined by the LAL method.
- Biological Activity Comment
- The ED50 is 10-20 ng/ml, corresponding to a specific activity of 1-0.5 x 10^5 units/mg, determined by the dose dependent stimulation of 3T3 cell proliferation. The bioactivity is equivalent to competitor reported values.
- Top Product
- Discover our top product PDGFRB 蛋白
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Platelet Derived Growth Factor Receptor beta (PDGFRB) (AA 33-530) protein (His-Avi Tag)
PDGFRB 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Platelet Derived Growth Factor Receptor beta (PDGFRB) (AA 33-531) protein (His tag)PDGFRB 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Platelet Derived Growth Factor Receptor beta (PDGFRB) protein (His-Avi Tag,Biotin)PDGFRB 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Platelet Derived Growth Factor Receptor beta (PDGFRB) (AA 33-133) protein (GST tag)PDGFRB 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Platelet Derived Growth Factor Receptor beta (PDGFRB) (Active) protein (His tag)PDGFRB 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
Platelet Derived Growth Factor Receptor beta (PDGFRB) (AA 33-532) protein (His tag)PDGFRB 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Platelet Derived Growth Factor Receptor beta (PDGFRB) (Active) protein (Fc Tag)PDGFRB 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays - 限制
- 仅限研究用
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- 浓度
- > 50 μg/mL
- 缓冲液
- 29 % acetonitrile, 0.1 % TFA (trifluoroacetic acid)
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))
- 别名
- Cd140b,pdgfrb (PDGFRB 产品)
- 别名
- AI528809 Protein, CD140b Protein, PDGFR-1 Protein, Pdgfr Protein, CD140B Protein, IBGC4 Protein, JTK12 Protein, PDGFR Protein, PDGFR1 Protein, platelet derived growth factor receptor, beta polypeptide Protein, platelet derived growth factor receptor beta Protein, Pdgfrb Protein, PDGFRB Protein
- 背景
- This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.
- 分子量
- 12.3 kDa
- NCBI登录号
- NP_002600
- 途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
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