P-Cadherin Protein (CDH3) (Myc-DYKDDDDK Tag)
Quick Overview for P-Cadherin Protein (CDH3) (Myc-DYKDDDDK Tag) (ABIN2713023)
抗原
See all P-Cadherin (CDH3) 蛋白蛋白类型
宿主
资源
应用范围
纯度
-
-
标记
- This P-Cadherin protein is labelled with Myc-DYKDDDDK Tag.
-
产品特性
-
- Recombinant human Cadherin-3 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
-
-
-
-
应用备注
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
说明
-
The tag is located at the C-terminal.
-
限制
- 仅限研究用
-
-
-
浓度
- 50 μg/mL
-
缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
-
储存条件
- -80 °C
-
储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
-
-
: "Identification of putative immunologic targets for colon cancer prevention based on conserved gene upregulation from preinvasive to malignant lesions." in: Cancer prevention research (Philadelphia, Pa.), Vol. 6, Issue 7, pp. 666-74, (2013) (PubMed).
-
: "Identification of putative immunologic targets for colon cancer prevention based on conserved gene upregulation from preinvasive to malignant lesions." in: Cancer prevention research (Philadelphia, Pa.), Vol. 6, Issue 7, pp. 666-74, (2013) (PubMed).
-
- P-Cadherin (CDH3)
-
别名
- Cadherin-3
-
背景
- This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene are associated with hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (EEMS).
-
分子量
- 88.8 kDa
-
NCBI登录号
- NP_001784
抗原
-