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Keratin 6 Protein (KRT6) (His tag)

KRT6 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2712834
发货至: 中国
  • 抗原 See all Keratin 6 (KRT6) products
    Keratin 6 (KRT6)
    蛋白类型
    Recombinant
    宿主
    资源
    大肠杆菌(E. Coli)
    标记
    This Keratin 6 protein is labelled with His tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human Cytokeratin 6 (full length, N-term HIS tag) protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the N-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Yang, Li, Tang, Lin, Wu, Bao: "Smartphone-Based Quantitative Analysis of Protein Array Signals for Biomarker Detection in Lupus." in: Chemosensors (Basel, Switzerland), Vol. 10, Issue 8, (2022) (PubMed).

  • 抗原
    Keratin 6 (KRT6)
    别名
    Cytokeratin 6 (KRT6 产品)
    别名
    Krt2-6 Protein, Krt-2.6 Protein, keratin 6 Protein, Krt6 Protein
    背景
    The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. This KRT6 gene in particular encodes the most abundant isoform. Mutations in these genes have been associated with pachyonychia congenita. In addition, peptides from the C-terminal region of the protein have antimicrobial activity against bacterial pathogens. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
    分子量
    60
    NCBI登录号
    NP_005545
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