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CYP17A1 Protein (Myc-DYKDDDDK Tag)

CYP17A1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2712752
发货至: 中国
  • 抗原 See all CYP17A1 蛋白
    CYP17A1 (Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 (CYP17A1))
    蛋白类型
    Recombinant
    宿主
    • 3
    • 2
    • 2
    资源
    • 3
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This CYP17A1 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human CYP17A1 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product CYP17A1 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    CYP17A1 (Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 (CYP17A1))
    别名
    Cyp17a1 (CYP17A1 产品)
    别名
    cyp17 Protein, CYPXVII Protein, P450c17 Protein, cyp17a1 Protein, P450-C17 Protein, wu:fi13g04 Protein, wu:fi17b11 Protein, wu:fi31c08 Protein, zgc:136516 Protein, zgc:66494 Protein, P45017A1 Protein, CYP17 Protein, CPT7 Protein, P450C17 Protein, S17AH Protein, Cyp17 Protein, p450c17 Protein, cytochrome P450 17A1 Protein, cytochrome P450, family 17, subfamily A, polypeptide 1 Protein, steroidogenic cytochrome P450 17-hydroxylase/lyase Protein, cytochrome P450 family 17 subfamily A member 1 L homeolog Protein, cytochrome P450 family 17 subfamily A member 1 Protein, cytochrome P-450 17 alpha-hydroxylase/C17,20-lyase Protein, cytochrome P450, family 17, subfamily a, polypeptide 1 Protein, cytochrome P450c17 Protein, CpipJ_CPIJ010537 Protein, CpipJ_CPIJ010543 Protein, PTRG_02047 Protein, cyp17a1 Protein, cyp17 Protein, cyp17a1.L Protein, CYP17A1 Protein, Cyp17a1 Protein
    背景
    This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia.
    分子量
    57.2 kDa
    NCBI登录号
    NP_000093
    途径
    Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, C21-Steroid Hormone Metabolic Process, Cellular Response to Molecule of Bacterial Origin
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