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CXCL12 Protein (Transcript Variant 1)

CXCL12 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 98 % , as determined by Coomassie stained SDS-PAGE. Func, AbP, STD, PI Active
产品编号 ABIN2712669
发货至: 中国
  • 抗原 See all CXCL12 蛋白
    CXCL12 (Chemokine (C-X-C Motif) Ligand 12 (CXCL12))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    Transcript Variant 1
    宿主
    • 24
    • 12
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    资源
    • 39
    • 3
    • 3
    • 1
    • 1
    大肠杆菌(E. Coli)
    应用范围
    Functional Studies (Func), Antibody Production (AbP), Standard (STD), Protein Interaction (PI)
    特异性
    Optimal preservation of protein structure, post-translational modifications and functions.
    产品特性
    • Recombinant human CXCL12 / SDF1 (transcript variant 1) protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
    • Tested for bioactivity.
    纯度
    > 98 % , as determined by Coomassie stained SDS-PAGE.
    内毒素水平
    Less than 0.1 EU/μg (<0.01 ng/μg) protein as determined by the LAL method.
    Biological Activity Comment
    The ED50 is 80 - 120 ng/ml, corresponding to a specific activity of 1.25-0.83 x 10^4 units/mg.
    Top Product
    Discover our top product CXCL12 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Protein-protein interaction
    In vitro biochemical assays and cell-based functional assays
    限制
    仅限研究用
  • 浓度
    > 50 μg/mL
    缓冲液
    20 mM Tris pH 8.0, 0.5M NaCl
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    CXCL12 (Chemokine (C-X-C Motif) Ligand 12 (CXCL12))
    别名
    Cxcl12,sdf1 (CXCL12 产品)
    背景
    This antimicrobial gene encodes a stromal cell-derived alpha chemokine member of the intercrine family. The encoded protein functions as the ligand for the G-protein coupled receptor, chemokine (C-X-C motif) receptor 4, and plays a role in many diverse cellular functions, including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene.
    分子量
    8.0 kDa
    NCBI登录号
    NP_954637
    途径
    Regulation of Cell Size, CXCR4-mediated Signaling Events, Negative Regulation of intrinsic apoptotic Signaling
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