Cullin 5 Protein (CUL5) (Myc-DYKDDDDK Tag)
This Recombinant Cullin 5 protein is expressed in HEK-293 Cells.
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Quick Overview for Cullin 5 Protein (CUL5) (Myc-DYKDDDDK Tag) (ABIN2712634)
抗原
See all Cullin 5 (CUL5) 蛋白
Cullin 5 (CUL5)
蛋白类型
Recombinant
宿主
人
资源
HEK-293 Cells
应用范围
Antibody Production (AbP), Standard (STD)
纯度
> 80 % as determined by SDS-PAGE and Coomassie blue staining
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标记
- This Cullin 5 protein is labelled with Myc-DYKDDDDK Tag.
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产品特性
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- Recombinant human Cullin-5 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Cullin 5 (CUL5) (AA 1-100) protein (GST tag)
CUL5 宿主: 人 宿主: 小麦胚 Recombinant ELISA, AA, AP, WB
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应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
说明
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The tag is located at the C-terminal.
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限制
- 仅限研究用
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浓度
- 50 μg/mL
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缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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储存条件
- -80 °C
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储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Cullin 5 (CUL5)
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别名
- Cullin-5
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背景
- Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein. May form a cell surface vasopressin receptor. [UniProtKB/Swiss-Prot Function]
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分子量
- 90.8 kDa
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NCBI登录号
- NP_003469
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途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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