ASH1L Protein (AA 2407-2579) (His tag,DYKDDDDK Tag)
This Recombinant ASH1L protein is expressed in 大肠杆菌（E. Coli）.
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产品编号 ABIN2669693
发货至:
中国
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Quick Overview for ASH1L Protein (AA 2407-2579) (His tag,DYKDDDDK Tag) (ABIN2669693)
抗原
ASH1L
(Ash1 (Absent, Small, Or Homeotic)-like (ASH1L))
蛋白类型
Recombinant
宿主
人
资源
大肠杆菌（E. Coli）
应用范围
Binding Studies (Bind), Screening Assay (ScA)
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产品特性
- AA 2407-2579
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标记
- This ASH1L protein is labelled with His tag,DYKDDDDK Tag.
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产品特性
- The peptide corresponding to amino acids 2407-2579 that contains the bromodomain sequences of ASH1L (accession number NP_060959.2) was expressed in E. coli and contains an N-terminal His tag and C-terminal FLAG tag with an observed molecular weight of 25.6 kDa.
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Ash1 (Absent, Small, Or Homeotic)-like (ASH1L) (AA 2433-2548) protein (His-IF2DI Tag)
ASH1L 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB
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应用备注
- Recombinant ASH1L (2407-2579) is suitable for use in binding assays, inhibitor screening, and selectivity profiling.
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限制
- 仅限研究用
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注意事项
- Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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储存条件
- -80 °C
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储存方法
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation.
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- ASH1L (Ash1 (Absent, Small, Or Homeotic)-like (ASH1L))
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别名
- ASH1L
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背景
- ASH1L is a member of the Trithorax group of transcriptional activators. The protein contains four AT hooks, a SET domain, a PHD-finger motif, and a bromodomain. The bromodomain functions as a 'reader' of epigenetic histone marks and regulates chromatin structure and gene expression by linking associated proteins to the recognized acetylated nucleosomal targets. ASH1L is localized to the nucleus and also to cell-cell tight junctions where it is hypothesized to function in adhesion-mediated signaling. ASH1L functions in methylation of H3K4 and regulation of expression of HOX genes and may possess methyltransferase activity directed at H3K36. ASH1L has also been implicated in facioscapulohumeral muscular dystrophy.
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分子量
- 25.6 kDa
抗原
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