CXCL5 Protein (AA 37-114)
Quick Overview for CXCL5 Protein (AA 37-114) (ABIN2666977)
抗原
See all CXCL5 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- AA 37-114
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内毒素水平
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Less than 0.01 ng per μg cytokine as determine by the LAL method.
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应用备注
- Optimal working dilution should be determined by the investigator.,Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Prior to use, reconstitute the lyophilized powder with 0.2 mLof PBS containing a carrier protein (e.g., 1 % BSA, protease free), pH 7.4. Re-cap vial, vortex. Allow the reconstituted standard to sit at room temperature for 15 minutes, vortex again to mix completely. The reconstituted standard stock solution can be aliquoted into polypropylene vials and stored at -70 °C for up to one month.
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缓冲液
- Lyophilized
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注意事项
- Use a manual defrost freezer and avoid repeated freeze thaw cycles.
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储存条件
- 4 °C
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储存方法
- Upon receipt, store unopened vials between 2°C and 8°C immediately and use within 12 months from date of receipt.
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有效期
- 12 months
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- CXCL5 (Chemokine (C-X-C Motif) Ligand 5 (CXCL5))
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别名
- CXCL5
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背景
- CXCL5 is a member of the CXC family of chemokines, also known as epithelial activated peptide 78 (ENA-78). The precursor of CXCL5 contains 114 amino acids, with a signal peptide of 36 amino acids which is cleaved to generate the 78 amino acid mature protein (8 kD). CXCL5 is expressed by monocytes/macrophages, endothelial cells, vascular smooth muscle cells, epithilial cells, and eosinophils. CXCL5 is an inflammatory cytokine which binds to the cell surface receptor CXCR2 and induces chemotaxis of neutrophils to a target site. High levels of CXCL5 have been associated with prostate, gastric, and pancreatic cancer progression.
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分子量
- The 78 amino acid recombinant protein has a predicted molecular mass of approximately 8.35 kDa. The DTT-reduced and non-reduced protein migrate at approximately 10 kDa by SDS-PAGE. The N-terminal amino acid is Ala.
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途径
- Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity
抗原
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