CCL19 Protein (AA 26-107)
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北京 101111
Quick Overview for CCL19 Protein (AA 26-107) (ABIN2666783)
抗原
See all CCL19 蛋白蛋白类型
生物活性
宿主
资源
应用范围
纯度
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产品特性
- AA 26-107
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过滤
- 0.22 μm filtered
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内毒素水平
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Less than 0.01 ng per μg cytokine as determined by the LAL method.
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Chemokine (C-C Motif) Ligand 19 (CCL19) (AA 26-108) protein (His-IF2DI Tag)
CCL19 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Chemokine (C-C Motif) Ligand 19 (CCL19) (AA 22-98) (Active) proteinCCL19 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 97 % by SDS PAGE CMA Active
Chemokine (C-C Motif) Ligand 19 (CCL19) (AA 1-98) protein (GST tag)CCL19 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Chemokine (C-C Motif) Ligand 19 (CCL19) (AA 22-98) protein (T7 tag)CCL19 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % SDS
Chemokine (C-C Motif) Ligand 19 (CCL19) (AA 22-98) protein (Fc Tag)CCL19 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Chemokine (C-C Motif) Ligand 19 (CCL19) (AA 22-98) (Active) protein (Biotin)CCL19 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 97 % by SDS PAGE CMA Active
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Biological activity: Bioactivity was measured by its property to chemoattract Baf3-hCCR7 transfectants in a dose dependent manner.
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限制
- 仅限研究用
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状态
- Liquid
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溶解方式
- For maximum results, quick spin vial prior to opening. Stock solutions should be prepared at no less than 10 μg/mL in sterile buffer (PBS, HPBS, DPBS, and EBSS) containing carrier protein such as 1 % BSA or HSA. After dilution, the cytokine can be stored between 2 °C and 8 °C for one month or from -20 °C to -70 °C for up to 3 months.
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缓冲液
- 0.22 μm filtered protein solution is in PBS.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Unopened vial can be stored between 2°C and 8°C for three months, at -20°C for six months, or at -70°C for one year.
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- CCL19 (Chemokine (C-C Motif) Ligand 19 (CCL19))
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别名
- CCL19
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背景
- CCL19 is a CC chemokine expressed in lymph nodes. CCL19 is only 32 % identical to CCL21 at the amino acid level, nevertheless, these chemokines bind to the same receptor: CCR7. CCL19 is not expressed in high endothelial venules (HEV) as CCL21, but CCL19 is transcytosed in HEV. It has been described that CCL19 binds to CCX-CKR and CRAM-B receptors. These two receptors are members of the non classical chemokine receptor family which, in addition, includes D6, DARC, and CXCR7. CCX-CKR has been suggested to be a scavenging receptor for CCL19, and CRAM-B receptor might be responsible for the transcytosis in HEV for CCL19. In addition, CRAM recycles constitutively, and can internalize CCL19 within a few minutes, suggesting an implication in the regulation of immune responses and homing processes.
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分子量
- The 84 amino acid recombinant protein has a predicted molecular mass of approximately 9.3 kDa. The DTT-reduced and non-reduced protein migrate from 12-20 kDa by SDS-PAGE. The N-terminal amino acid is Gly.
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途径
- Positive Regulation of Immune Effector Process
抗原
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