CXCL11 Protein (AA 22-100)
Quick Overview for CXCL11 Protein (AA 22-100) (ABIN2666636)
抗原
See all CXCL11 蛋白蛋白类型
生物活性
宿主
资源
应用范围
纯度
-
-
产品特性
- AA 22-100
-
过滤
- 0.22 μm filtered
-
内毒素水平
-
Less than 0.01 ng per μg cytokine as determined by the LAL method.
-
-
Chemokine (C-X-C Motif) Ligand 11 (CXCL11) (Active) protein
CXCL11 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Chemokine (C-X-C Motif) Ligand 11 (CXCL11) (AA 1-94) protein (GST tag)CXCL11 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Chemokine (C-X-C Motif) Ligand 11 (CXCL11) (AA 22-98), (partial) protein (His tag)CXCL11 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant 90 % SDS, ELISA
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
说明
-
Biological activity: Bioactivity was measured by its property to chemoattract Baf3-hCXCR3 transfectants in a dose dependent manner.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
溶解方式
- For maximum results, quick spin vial prior to opening. The protein can be aliquoted and stored from -20 °C to -70 °C. Stock solutions can also be prepared at 50-100 μg/mL in sterile buffer (PBS, HPBS, DPBS, or EBSS) containing carrier protein such as 0.2-1 % BSA or HSA and stored in working aliquots at -20 °C to -70 °C.
-
缓冲液
- 0.22 μm filtered protein solution is in PBS.
-
注意事项
- Avoid repeated freeze/thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- Unopened vial can be stored between 2°C and 8°C for one month, at -20°C for six months, or at -70°C for one year.
-
-
- CXCL11 (Chemokine (C-X-C Motif) Ligand 11 (CXCL11))
-
别名
- CXCL11
-
背景
- CXCL11 is a CXC chemokine lacking the ELR (Glutamate-Leucine-Arginine) tripeptide motif, which is functionally and structurally related to CXCL9 and CXCL10. CXCL11, together with CXCL9 and CXCL10, specifically binds to the G protein-coupled receptor CXCR3 and is involved in chemotaxis of immune cells and angiogenesis. Expression of both CXCR3 and CXCL11 by the Th1-associated cytokine IFNγ creates an amplification loop of cell-mediated immune response between Th1 cells. CXCR7 has been identified as an alternate receptor for CXCL11 and is involved in growth, survival, and adhesion of tumor cells.
-
分子量
- The 80 amino acid recombinant protein has a predicted molecular mass of approximately 9.1 kDa. The DTT-reduced protein migrates at approximately 11 kDa and non-reduced protein migrates at approximately 13 kDa by SDS-PAGE. The N-terminal amino acid is Meth
抗原
-
