Osteoactivin Protein (GPNMB) (His tag)
Quick Overview for Osteoactivin Protein (GPNMB) (His tag) (ABIN2566817)
抗原
See all Osteoactivin (GPNMB) 蛋白蛋白类型
生物活性
宿主
资源
应用范围
纯度
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标记
- This Osteoactivin protein is labelled with His tag.
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产品特性
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Measured by the ability of the immobilized protein to induce pro-MMP-9 secretion by NHLF human normal lung fibroblasts. The ED50 for this effect is typically 4 - 16 μg/mL.
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Osteoactivin (GPNMB) (AA 23-496) protein (His tag)
GPNMB 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Osteoactivin (GPNMB) (AA 23-486) protein (His tag)GPNMB 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Osteoactivin (GPNMB) (AA 23-502) protein (His tag)GPNMB 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Osteoactivin (GPNMB) (AA 1-572) protein (GST tag)GPNMB 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Osteoactivin (GPNMB) (AA 22-474) protein (His tag)GPNMB 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 90 % SDS
Osteoactivin (GPNMB) (AA 22-474) protein (His tag)GPNMB 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 85 % SDS
Osteoactivin (GPNMB) protein (His tag)GPNMB 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
Osteoactivin (GPNMB) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)GPNMB 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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应用备注
- This recombinant protein can be used for WB. For research use only.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- PBS, pH 7.4
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储存条件
- -80 °C,-20 °C
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储存方法
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
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- Osteoactivin (GPNMB)
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别名
- Osteoactivin
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背景
- Transmembrane glycoprotein NMB (GPNMB) is also known as Transmembrane glycoprotein HGFIN, DC-HIL and Osteoactivin (OA), which belongs to the PMEL/NMB family. GPNMB contains one PKD domain. GPNMB is a transmembrane glycoprotein that is up-regulated in various cancer cells, including in glioblastoma multiforme and is expressed in many melanoma cells, as well as in tissue macrophages. GPNMB protein acts as a downstream mediator of BMP-2 effects on osteoblast differentiation and function. GPNMB participates in bone mineralization, and functions as a negative regulator of inflammation in macrophages.
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分子量
- 52.9 kDa
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基因ID
- 10457
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UniProt
- Q14956
抗原
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