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CD58 Protein (CD58) (His tag)

CD58 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. WB Active
产品编号 ABIN2566429
发货至: 中国
  • 抗原 See all CD58 蛋白
    CD58
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    资源
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This CD58 protein is labelled with His tag.
    应用范围
    Western Blotting (WB)
    产品特性

    Measured in a cell proliferation assay using human CD3+ T cells in the presence of anti-CD3. The ED50 for this effect is typically 1 - 5 μg/mL in the presence of anti-CD3 immobilized at 25 ng/mL.

    纯度
    >95 % as determined by SDS-PAGE.
    Top Product
    Discover our top product CD58 蛋白
  • 应用备注
    This recombinant protein can be used for WB. For research use only.
    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS, pH 7.4
    储存条件
    -80 °C,-20 °C
    储存方法
    Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
  • 抗原
    CD58
    别名
    CD58 (CD58 产品)
    别名
    LFA-3 Protein, LFA3 Protein, ag3 Protein, CD58 molecule Protein, CD58 Protein
    背景
    CD antigen CD58 is also known as Lymphocyte function-associated antigen 3 (LFA-3). CD58 is a cell adhesion molecule expressed on Antigen Presenting Cells (APC), particularly macrophages. CD58 /LFA3 is ligand of the T-lymphocyte CD2 glycoprotein, which binds to CD2 (LFA-2) [3] on T cells and is important in strengthening the adhesion between the T cells and Professional Antigen Presenting Cells. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells. Polymorphisms in the CD58 gene are associated with increased risk for multiple sclerosis.
    分子量
    22.3 kDa
    基因ID
    965
    UniProt
    P19256
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