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Resistin Protein (RETN)

This Recombinant Resistin protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN2469020
发货至: 中国

Quick Overview for Resistin Protein (RETN) (ABIN2469020)

抗原

See all Resistin (RETN) 蛋白
Resistin (RETN)

蛋白类型

Recombinant

宿主

  • 19
  • 7
  • 3
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  • 1
大鼠

资源

  • 19
  • 8
  • 1
  • 1
大肠杆菌(E. Coli)

纯度

< 97 % by SDS-PAGE gel and HPLC analyses.
  • 序列

    MPSMSLCPMD EAISKKINQD FSSLLPAAMK NTVLHCWSVS SRGRLASCPE GTTVTSCSCG SGCGSWDVRE DTMCHCQCGS IDWTAARCCT LRVGS

    内毒素水平

    Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    注意事项

    As with any protein, exposing Resistin recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

    储存条件

    -20 °C

    储存方法

    The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted Resistin is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.

    有效期

    24 months
  • 抗原

    Resistin (RETN)

    别名

    Resistin

    背景

    Resistin belongs to a family of tissue-specific cytokines termed FIZZ (found in inflammatory zones) and RELM. The three known members of this family , Resistin, RELM-alpha and RELM-beta share a highly conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. Resistin is an adipose-derived cytokine (adipokine) whose physiological function and molecular targets are largely unknown. Studies have shown that Resistin suppresses insulin s ability to stimulate glucose uptake, and postulated that Resistin might be an important link between obesity and Type 2 diabetes. Other studies have indicated that Resistin expression is severely suppressed in obesity and that it may act as a feedback regulator of Adipogenesis. Recombinant rat Resistin is a 20.0 kDa disulfide-linked homodimeric protein composed of two 94 identical amino acid chains linked by a single disulfide bond.

    基因ID

    246250

    NCBI登录号

    NP_653342

    OMIM

    21426805

    UniProt

    Q8K4J7

    途径

    Feeding Behaviour, Smooth Muscle Cell Migration
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