alpha Defensin 1 蛋白
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北京 101111
Quick Overview for alpha Defensin 1 蛋白 (ABIN2468909)
抗原
See all alpha Defensin 1 (DEFA1) 蛋白蛋白类型
生物活性
宿主
资源
纯度
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序列
- ACYCRIPACI AGERRYGYCI YQGRLWAFCC
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产品特性
- Determined by its ability to induce adhesion of HUVECs. The expected ED50 for this effect is 1.5- 2.5 μg/ml.
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内毒素水平
- Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
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限制
- 仅限研究用
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状态
- Lyophilized
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注意事项
- As with any protein, exposing NP-1 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
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储存条件
- -20 °C
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储存方法
- The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted NP-1 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
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有效期
- 24 months
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- alpha Defensin 1 (DEFA1) (Defensin, alpha 1 (DEFA1))
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别名
- alpha Defensin-1
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背景
- Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The α-defensins which include NP-1, NP-2 and NP-3, are distinguished from the beta-defensins by the pairing of their three disulfide bonds. In addition to antimicrobial activity, NP-1 exhibits chemotactic activity on dendritic cells. NP-1 is expressed as the C-terminal portion of an inactive precursor protein, which also contains a 19 amino acid N-terminal signal sequence and a 45 amino acid polypeptide. NP-1 contains a six-cysteine motif that forms three intra-molecular disulfide bonds. Recombinant human NP-1 is a 3.4 kDa protein containing 30 amino acid residues.
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基因ID
- 1667
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NCBI登录号
- NP_004075
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OMIM
- 4758146
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UniProt
- P59665
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途径
- Cellular Response to Molecule of Bacterial Origin
抗原
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