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alpha Defensin 1 蛋白

This Recombinant alpha Defensin 1 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN2468909
发货至: 中国
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Quick Overview for alpha Defensin 1 蛋白 (ABIN2468909)

抗原

See all alpha Defensin 1 (DEFA1) 蛋白
alpha Defensin 1 (DEFA1) (Defensin, alpha 1 (DEFA1))

蛋白类型

Recombinant

生物活性

Active

宿主

  • 6
  • 1
  • 1
  • 1

资源

  • 3
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大肠杆菌(E. Coli)

纯度

< 98 % by SDS-PAGE gel and HPLC analyses.
  • 序列

    ACYCRIPACI AGERRYGYCI YQGRLWAFCC

    产品特性

    Determined by its ability to induce adhesion of HUVECs. The expected ED50 for this effect is 1.5- 2.5 μg/ml.

    内毒素水平

    Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    注意事项

    As with any protein, exposing NP-1 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

    储存条件

    -20 °C

    储存方法

    The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted NP-1 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.

    有效期

    24 months
  • 抗原

    alpha Defensin 1 (DEFA1) (Defensin, alpha 1 (DEFA1))

    别名

    alpha Defensin-1

    背景

    Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The α-defensins which include NP-1, NP-2 and NP-3, are distinguished from the beta-defensins by the pairing of their three disulfide bonds. In addition to antimicrobial activity, NP-1 exhibits chemotactic activity on dendritic cells. NP-1 is expressed as the C-terminal portion of an inactive precursor protein, which also contains a 19 amino acid N-terminal signal sequence and a 45 amino acid polypeptide. NP-1 contains a six-cysteine motif that forms three intra-molecular disulfide bonds. Recombinant human NP-1 is a 3.4 kDa protein containing 30 amino acid residues.

    基因ID

    1667

    NCBI登录号

    NP_004075

    OMIM

    4758146

    UniProt

    P59665

    途径

    Cellular Response to Molecule of Bacterial Origin
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