Hemagglutinin Protein (HA) (AA 17-338) (His tag,Strep II tag)
Quick Overview for Hemagglutinin Protein (HA) (AA 17-338) (His tag,Strep II tag) (ABIN2468516)
抗原
See all Hemagglutinin (HA) 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- AA 17-338
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标记
- This Hemagglutinin protein is labelled with His tag,Strep II tag.
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Hemagglutinin (HA) (AA 17-338) protein (His tag)
HA 宿主: Influenza A Virus H5N1 宿主: Baculovirus infected Insect Cells Recombinant > 90% by SDS-PAGE SDS
Hemagglutinin (HA) (AA 18-344) protein (His tag)HA 宿主: Influenza A Virus H1N1 宿主: Baculovirus infected Insect Cells Recombinant > 90% by SDS-PAGE SDS
Hemagglutinin (HA) (AA 17-531) protein (His tag)HA 宿主: Influenza Virus 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
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应用备注
- This recombinant protein can be used for WB, ELISA, MS.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 1X PBS containing 0.1 % SDS and 0.02 % NaN
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
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储存条件
- -80 °C
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储存方法
- Store in working aliquots at -70 °C.
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- Hemagglutinin (HA)
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别名
- Hemagglutinin
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物质类
- Influenza Protein
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背景
- Influenza A virus is a major public health threat, killing more than 30,000 people per year in the USA (1). Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals, but it is in birds that all subtypes can be found (2). These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. HA interacts with host cell surface proteins containing oligosaccharides with terminal sialyl residues. Its extracellular region has two domains (HA1 and HA2) , HA1 is cleaved from the main hemagglutinin protein by the host immune system. During 1997, an H5N1 avian influenza virus was determined to be the cause of death in 6 of 18 infected patients in Hong Kong (3). This more recent virulent strain of H5N1 is now seen in Africa and Europe, as well as in Southeast Asia. There is some evidence of human to human spread of this virus, but it is thought that the efficiency of this type of transmission is low (4). Virus isolated from a human infected with the H5N1 strain in 1997 could bind to oligosaccharides from human as well as avian sources, indicating its species-jumping ability (5). This HA1 recombinant protein is recognized by several ProSci hemagglutinin antibodies.
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分子量
- 39 kDa (Calculated)
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基因ID
- 3654620
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OMIM
- 50365729
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UniProt
- Q692M2
抗原
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