GM-CSF 蛋白
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北京 101111
Quick Overview for GM-CSF 蛋白 (ABIN2468495)
抗原
See all GM-CSF (CSF2) 蛋白蛋白类型
生物活性
宿主
资源
纯度
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序列
- MAPTRSPNPV TRPWKHVDAI KEALSLLNDM RALENEKNED VDIISNEFSI QRPTCVQTRL KLYKQGLRGN LTKLNGALTM IASHYQTNCP PTPETDCEIE VTTFEDFIKN LKGFLFDIPF DCWKPVQK
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产品特性
- The ED50 was determined by the dose - dependent stimulation of the proliferation of Murine FDC - P1 cells is < 0.01 ng/mL, corresponding to a specific activity of > 1.0 x 108 units/mg.
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内毒素水平
- Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
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限制
- 仅限研究用
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状态
- Lyophilized
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注意事项
- As with any protein, exposing GM-CSF recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
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储存条件
- -20 °C
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储存方法
- The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted GM-CSF is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
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有效期
- 24 months
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- GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))
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别名
- GM-CSF
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背景
- GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in by endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and murine molecules are species-specific and exhibit no cross-species reactivity. Recombinant rat GM-CSF is a 14.5 kDa globular protein consisting of 128 amino acids residues.
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基因ID
- 116630
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NCBI登录号
- NP_446304
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OMIM
- 449083355
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UniProt
- P48750
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途径
- JAK/STAT Signaling, Cellular Response to Molecule of Bacterial Origin
抗原
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