GDF5 蛋白
Our Local Distributor
北京 101111
Quick Overview for GDF5 蛋白 (ABIN2468474)
抗原
See all GDF5 蛋白蛋白类型
生物活性
宿主
资源
纯度
-
-
序列
- APLANRQGKR PSKNLKARCS RKALHVNFKD MGWDDWIIAP LEYEAFHCEG LCEFPLRSHL EPTNHAVIQT LMNSMDPEST PPTCCVPTRL SPISILFIDS ANNVVYKQYE DMVVESCGCR
-
产品特性
- Endotoxin level is less than 0.1 ng per μg (1EU/μg).
-
内毒素水平
- Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
-
-
-
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
注意事项
- As with any protein, exposing GDF-5 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
-
储存条件
- -20 °C
-
储存方法
- The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted GDF-5 stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
-
有效期
- 24 months
-
-
- GDF5 (Growth Differentiation Factor 5 (GDF5))
-
别名
- GDF-5
-
背景
- GDF-5 is expressed in long bones during embryonic development and postnatally in articular cartilage. Mutations in the GDF-5 gene have been implicated in Grebe Syndrome, which is characterized by short stature, extra digits, short and deformed extremities, and in Hunter-Thompson type dwarfism. The mature and functional form of GDF-5 is a homodimer of two 120 amino-acid polypeptide chain (monomers) linked by a single disulfide bond. Each GDF-5 monomer is expressed as the C-terminal part of a precursor polypeptide, which also contains a 27 amino-acid signal peptide and a 348 amino-acid propeptide. This precursor undergoes intracellular dimerization, and upon secretion it is processed by a furin-type protease. Recombinant murine GDF-5 is a 27.0 kDa homodimeric disulfide-linked protein consisting of two 120 amino acids.
-
基因ID
- 8200
-
NCBI登录号
- NP_000548
-
OMIM
- 4503969
-
UniProt
- P43026
抗原
-