Calreticulin Protein (CALR) (AA 18-417)
Quick Overview for Calreticulin Protein (CALR) (AA 18-417) (ABIN2468306)
抗原
See all Calreticulin (CALR) 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- AA 18-417
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Calreticulin (CALR) protein (His tag)
CALR 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >90 % (SDS-PAGE) SDS
Calreticulin (CALR) (AA 25-199) protein (His-IF2DI Tag)CALR 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % by SDS-PAGE gel analyses WB, ELISA
Calreticulin (CALR) (AA 1-417) protein (GST tag)CALR 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Calreticulin (CALR) (AA 18-417) protein (His tag)CALR 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 85 % by SDS - PAGE SDS
Calreticulin (CALR) (AA 18-417) protein (His tag)CALR 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
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应用备注
- This recombinant protein can be used for WB, ELISA, MS.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 10 mM Tris, pH 8.0, 0.002 % NaN, 3 mM NaCl, 2.5 mM
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
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储存条件
- -80 °C
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储存方法
- Store in working aliquots at -70 °C.
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- Calreticulin (CALR)
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别名
- CALR
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背景
- Calreticulin is a multifunctional protein that acts as a major Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. It is also found in the nucleus, suggesting that it may have a role in transcription regulation. Calreticulin binds to the synthetic peptide KLGFFKR, which is almost identical to an amino acid sequence in the DNA-binding domain of the superfamily of nuclear receptors. Calreticulin binds to antibodies in certain sera of systemic lupus and Sjogren patients which contain anti-Ro/SSA antibodies, it is highly conserved among species, and it is located in the endoplasmic and sarcoplasmic reticulum where it may bind calcium.
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分子量
- 46 kDa (Calculated)
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基因ID
- 811
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NCBI登录号
- NP_004334
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OMIM
- 4757900
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UniProt
- P27797
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途径
- Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, ER-Nucleus Signaling, Unfolded Protein Response
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