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Calreticulin Protein (CALR) (AA 18-417)

This Recombinant Calreticulin protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN2468306
发货至: 中国

Quick Overview for Calreticulin Protein (CALR) (AA 18-417) (ABIN2468306)

抗原

See all Calreticulin (CALR) 蛋白
Calreticulin (CALR)

蛋白类型

Recombinant

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资源

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大肠杆菌(E. Coli)

应用范围

Western Blotting (WB), ELISA, Mass Spectrometry (MS)

纯度

~90 %
  • 产品特性

    AA 18-417
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  • 应用备注

    This recombinant protein can be used for WB, ELISA, MS.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    10 mM Tris, pH 8.0, 0.002 % NaN, 3 mM NaCl, 2.5 mM

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

    储存条件

    -80 °C

    储存方法

    Store in working aliquots at -70 °C.
  • 抗原

    Calreticulin (CALR)

    别名

    CALR

    背景

    Calreticulin is a multifunctional protein that acts as a major Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. It is also found in the nucleus, suggesting that it may have a role in transcription regulation. Calreticulin binds to the synthetic peptide KLGFFKR, which is almost identical to an amino acid sequence in the DNA-binding domain of the superfamily of nuclear receptors. Calreticulin binds to antibodies in certain sera of systemic lupus and Sjogren patients which contain anti-Ro/SSA antibodies, it is highly conserved among species, and it is located in the endoplasmic and sarcoplasmic reticulum where it may bind calcium.

    分子量

    46 kDa (Calculated)

    基因ID

    811

    NCBI登录号

    NP_004334

    OMIM

    4757900

    UniProt

    P27797

    途径

    Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, ER-Nucleus Signaling, Unfolded Protein Response
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