BMP5 蛋白
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- 抗原 See all BMP5 蛋白
- BMP5 (Bone Morphogenetic Protein 5 (BMP5))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- CHO Cells
- 序列
- AANKRKNQNR NKSSSHQDSS RMSSVGDYNT SEQKQACKKH ELYVSFRDLG WQDWIIAPEG YAAFYCDGEC SFPLNAHMNA TNHAIVQTLV HLMFPDHVPK PCCAPTKLNA ISVLYFDDSS NVILKKYRNM VVRSCGCH
- 产品特性
- Biological activity was determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 1.0-2.0 μg/mL.
- 纯度
- < 95 % by SDS-PAGE gel and HPLC analyses.
- 内毒素水平
- Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
- Top Product
- Discover our top product BMP5 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 注意事项
- As with any protein, exposing BMP-5 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
- 储存条件
- -20 °C
- 储存方法
- The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted BMP-5 stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
- 有效期
- 24 months
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- 抗原
- BMP5 (Bone Morphogenetic Protein 5 (BMP5))
- 别名
- BMP-5 (BMP5 产品)
- 别名
- bmp5l Protein, hm:zehl0669 Protein, zehl0669 Protein, zgc:64230 Protein, BMP5 Protein, AU023399 Protein, se Protein, bone morphogenetic protein 5 Protein, bmp5 Protein, BMP5 Protein, LOC100539495 Protein, Bmp5 Protein
- 背景
- TGF-beta family members are key modulators of cell proliferation, differentiation, matrix synthesis, and apoptosis. As implied by their name, BMPs initiate, promote, and regulate the development, growth and remodeling of bone and cartilage. In addition to this role, BMPs are also involved in prenatal development and postnatal growth, remodeling and maintenance of a variety of other tissues and organs. BMP-5 is expressed in the nervous system, lung and liver. It is a known regulator for dendritic growth in sympathetic neurons. BMP-5 is a 454 amino acid precursor protein that is cleaved to release the biologically active C-terminal mature protein. Recombinant human BMP-5 is a 31.2 kDa homodimeric disulfide-linked protein consisting of two identical 138 amino acid chains.
- 基因ID
- 653
- NCBI登录号
- NP_066551
- OMIM
- 10835091
- UniProt
- P22003
- 途径
- Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process
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