BMP4 蛋白
This Recombinant BMP4 protein is expressed in 大肠杆菌（E. Coli）.
Quick Overview for BMP4 蛋白 (ABIN2468290)
抗原
See all BMP4 蛋白
BMP4
(Bone Morphogenetic Protein 4 (BMP4))
蛋白类型
Recombinant
生物活性
Active
宿主
小鼠
资源
大肠杆菌（E. Coli）
纯度
< 98 % by SDS-PAGE gel and HPLC analyses.
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序列
- KKNKNCRRHS LYVDFSDVGW NDWIVAPPGY QAFYCHGDCP FPLADHLNST NHAIVQTLVN SVNSSIPKAC CVPTELSAIS MLYLDEYDKV VLKNYQEMVV EGCGCRKKNK NCRRHSLYVD FSDVGWNDWI VAPPGYQAFY CHGDCPFPLA DHLNSTNHAI VQTLVNSVNS SIPKACCVPT ELSAISMLYL DEYDKVVLKN YQEMVVEGCG CR
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产品特性
- Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 5-15 ng/mL.
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Bone Morphogenetic Protein 4 (BMP4) (AA 303-408) protein (His-IF2DI Tag)
BMP4 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Bone Morphogenetic Protein 4 (BMP4) (AA 293-408) proteinBMP4 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % by SDS - PAGE SDS
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限制
- 仅限研究用
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状态
- Lyophilized
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注意事项
- As with any protein, exposing BMP-4 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
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储存条件
- -20 °C
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储存方法
- The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted BMP-4 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
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有效期
- 24 months
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- BMP4 (Bone Morphogenetic Protein 4 (BMP4))
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别名
- BMP-4
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背景
- Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-beta superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body and are involved in diverse physiological processes during both pre- and postnatal life. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. PeproTech s E.coli derived murine BMP-4 is a fully active homodimeric protein consisting of two 106 amino acid subunits which correspond to amino acids 303-408 of the full length BMP-4 precursor.
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基因ID
- 12159
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NCBI登录号
- NP_031580
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OMIM
- 121949823
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UniProt
- P21275
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途径
- Steroid Hormone Mediated Signaling Pathway, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
抗原
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